I-CAS: 77472-71-0 2-Oxo-4-Phenyl-1-Pyrrolidineacetic Acid Hydrazide Phenylpiracetam hydrazine

I-N-formyl derivative 4 itholwe nge-reflux ye-2 ku-formic acid amahora angu-5 ngesivuno esiphezulu.I-acetic acid N'-[2-(7-hydroxy-2-oxo-2 H-chromen-4-yl)-acetyl]-hydrazide (5) itholwe nge-reflux acetylation ye-2 ku-acetic acid ngesivuno esihle.I-Compound 6 iphinde itholakale ngokubuyisela kabusha i-2 nge-3-(2-bromoacetyl) -4-hydroxy-2 H-chromen-2-one ku-ethanol.Inhlanganisela engu-2 ihlangana ne-phenyl isothiocyanate ku-ethanol kuzinga lokushisa legumbi ukuze ithole i-4-phenyl-1-(7-hydroxy-2-oxo-2 H-chromen-4-acetyl -)-thiosemicarbazide (7).
3-{2-[2-(7-hydroxy-2-oxo-2 H-chromen-4-yl)-acetyl]hydrazono}butanoate (8) ethyl ester (8), 3-{2-[2-( 7-hydroxy-2-oxo-2 H-Chromen-4-yl)-acetyl] Hydrazono} Butanoate (8), Isivuno sibe ngu-48% (Inketho 2).Isakhiwo sezinhlanganisela 4-8 sinqunywe idatha yabo yokuhlaziya kanye ne-IR yabo ne-1 H-NMR spectra.Ukumuncwa kwe-infrared ngenxa yemisebenzi ye-NH, OH kanye ne-C=O ivela ku-3450-3000 naku-1728-1610cm-1, ngokulandelanayo.Amabhendi okumuncwa ahlobene nokuba khona kwamanye amaqembu asebenzayo akhona endaweni elindelekile.I-spectrum ye-1 H-NMR ye-compound ibonisa ukuphakama okukodwa esifundeni se-8.03-10.58ppm esihambisana ne-NH ne-OH protons.Inhlanganisela 4-8