CAS: 77472-71-0 2-Oxo-4-Phenyl-1-Pyrrolidineacetic Acid Hydrazide Phenylpiracetam hydrazine

N-formyl derivative 4 e fumanoe ka reflux ea 2 ka formic acid bakeng sa lihora tse 5 ka lihlahisoa tse ngata.Acetic acid N'-[2- (7-hydroxy-2-oxo-2 H-chromen-4-yl) -acetyl] -hydrazide (5) e fumanoe ka reflux acetylation ea 2 ka acetic acid ka lihlahisoa tse ntle.Compound 6 e boetse e fumanoa ka refluxing 2 le 3-(2-bromoacetyl) -4-hydroxy-2 H-chromen-2-one ka ethanol.Compound 2 e sebetsana le phenyl isothiocyanate ka ethanol mocheso oa kamore ho fumana 4-phenyl-1-(7-hydroxy-2-oxo-2 H-chromen-4-acetyl -)-thiosemicarbazide (7).
3-{2-[2-(7-hydroxy-2-oxo-2 H-chromen-4-yl)-acetyl]hydrazono}butanoate (8) ethyl ester (8), 3-{2-[2-( 7-hydroxy-2-oxo-2 H-Chromen-4-yl)-acetyl] Hydrazono} Butanoate (8), Theko e ne e le 48% (Kgetho 2).Sebopeho sa metsoako ea 4-8 se ne se khethoa ke lintlha tsa bona tsa tlhahlobo le IR le 1 H-NMR spectra.Ho monya ha infrared ka lebaka la mesebetsi ea NH, OH le C=O ho hlaha ho 3450-3000 le 1728-1610cm-1, ka ho latellana.Lihlopha tsa ho monya tse amanang le boteng ba lihlopha tse ling tse sebetsang li teng sebakeng se lebeletsoeng.Sehlopha sa 1 H-NMR sa motsoako se bontša tlhōrō e le 'ngoe sebakeng sa 8.03-10.58ppm se lumellanang le NH le OH protons.Motsoako oa 4-8