CAS: 77472-71-0 2-Oxo-4-Phenyl-1-Pyrrolidineacetic Acid Hydrazide Phenylpiracetam hydrazine

An samo asalin N-formyl 4 ta reflux na 2 a cikin formic acid na tsawon sa'o'i 5 a babban yawan amfanin ƙasa.Acetic acid N'-[2- (7-hydroxy-2-oxo-2 H-chromen-4-yl) -acetyl] -hydrazide (5) an samu ta hanyar reflux acetylation na 2 a cikin acetic acid a kyakkyawan yawan amfanin ƙasa.Hakanan ana samun haɗin 6 ta hanyar refluxing 2 tare da 3- (2-bromoacetyl) -4-hydroxy-2 H-chromen-2-one a cikin ethanol.Haɗin 2 yana amsawa tare da phenyl isothiocyanate a cikin ethanol a zafin jiki don samun 4-phenyl-1- (7-hydroxy-2-oxo-2 H-chromen-4-acetyl -) - thiosemicarbazide (7).
3-{2-[2-(7-hydroxy-2-oxo-2 H-chromen-4-yl)-acetyl]hydrazono}butanoate (8) ethyl ester (8), 3-{2-[2-( 7-hydroxy-2-oxo-2 H-Chromen-4-yl)-acetyl] Hydrazono} Butanoate (8), Yawan amfanin ƙasa shine 48% (Zaɓi 2).Tsarin mahadi 4-8 an ƙaddara ta hanyar bayanan nazarin su da IR da 1 H-NMR.Ƙunƙarar infrared saboda ayyukan NH, OH da C = O yana bayyana a 3450-3000 da 1728-1610cm-1, bi da bi.Ƙungiyoyin shaye-shaye masu alaƙa da kasancewar sauran ƙungiyoyi masu aiki suna nan a yankin da ake sa ran.Bakan 1 H-NMR na fili yana nuna kololuwa guda ɗaya a cikin yankin 8.03-10.58ppm wanda ya dace da NH da protons OH.Haɗin gwiwa 4-8