CAS: 77472-71-0 2-Oxo-4-Phenyl-1-Pyrrolidineacetic Acid Hydrazide Phenylpiracetam hydrazine

N-formyl derivative 4 waxaa lagu helay reflux of 2 in formic acid muddo 5 saacadood ah wax soo saarka sare.Acid Acetic N'-[2- (7-hydroxy-2-oxo-2 H-chromen-4-yl) -acetyl] -hydrazide (5) waxaa lagu helay reflux acetylation of 2 ee acetic acid soo saarid wanaagsan.Isku-dhafka 6 ayaa sidoo kale lagu helaa dib-u-celinta 2 oo leh 3- (2-bromoacetyl) -4-hydroxy-2 H-chromen-2-one ee ethanol.Isku-dhafka 2 wuxuu la falgalaa phenyl isothiocyanate ee ethanol heerkulka qolka si loo helo 4-phenyl-1- (7-hydroxy-2-oxo-2 H-chromen-4-acetyl -) - thiosemicarbazide (7).
3-{2-[2-(7-hydroxy-2-oxo-2 H-chromen-4-yl)-acetyl]hydrazono}butanoate (8) ethyl ester (8), 3-{2-[2- 7-hydroxy-2-oxo-2 H-Chromen-4-yl)-acetyl] Hydrazono} Butanoate (8), Wax-soo-saarku wuxuu ahaa 48% (Doorashada 2).Qaab dhismeedka xeryahooda 4-8 waxaa lagu go'aamiyay xogtooda falanqaynta iyo IR iyo 1 H-NMR spectra.Nuugista infrared-ka ee ay sabab u tahay NH, OH iyo C=O shaqooyinka waxay ka muuqdaan 3450-3000 iyo 1728-1610cm-1, siday u kala horreeyaan.Qaybaha nuugista ee la xidhiidha joogitaanka kooxaha kale ee shaqada ayaa jooga gobolka la filayo.Baaxadda 1 H-NMR ee xaruntu waxay muujinaysaa hal ugu sarreeya gobolka 8.03-10.58ppm ee u dhiganta NH iyo OH protons.Isku dhafka 4-8