CAS: 77472-71-0 2-Oxo-4-Phenyl-1-Pyrrolidineacetic Acid Hydrazide Phenylpiracetam hydrazine

N-formyl yotengedwa 4 inapezedwa ndi reflux ya 2 mu formic acid kwa maola 5 pa zokolola zambiri.Acetic acid N'- [2- (7-hydroxy-2-oxo-2 H-chromen-4-yl) -acetyl] -hydrazide (5) inapezedwa ndi reflux acetylation ya 2 mu acetic acid pa zokolola zabwino.Compound 6 imapezedwanso ndi refluxing 2 ndi 3-(2-bromoacetyl) -4-hydroxy-2 H-chromen-2-imodzi mu ethanol.Compound 2 imakhudzidwa ndi phenyl isothiocyanate mu ethanol kutentha kwa firiji kuti ipeze 4-phenyl-1-(7-hydroxy-2-oxo-2 H-chromen-4-acetyl -) -thiosemicarbazide (7).
3-{2-[2-(7-hydroxy-2-oxo-2 H-chromen-4-yl)-acetyl]hydrazono}butanoate (8) ethyl ester (8), 3-{2-[2-( 7-hydroxy-2-oxo-2 H-Chromen-4-yl)-acetyl] Hydrazono} Butanoate (8), Zokolola zinali 48% (Njira 2).Mapangidwe a mankhwala 4-8 adatsimikiziridwa ndi deta yawo yowunikira komanso mawonekedwe awo a IR ndi 1 H-NMR.Mayamwidwe a infuraredi chifukwa cha ntchito za NH, OH ndi C=O zimawoneka pa 3450-3000 ndi 1728-1610cm-1, motsatana.Magulu a mayamwidwe okhudzana ndi kukhalapo kwa magulu ena ogwira ntchito amapezeka m'dera lomwe likuyembekezeredwa.Chiwonetsero cha 1 H-NMR chapawiri chikuwonetsa nsonga imodzi m'dera la 8.03-10.58ppm lofanana ndi ma protoni a NH ndi OH.Konzani 4-8