CAS: 77472-71-0 2-Oxo-4-Phenyl-1-Pyrrolidineacetic Acid Hydrazide Phenylpiracetam hydrazine

O le N-formyl derivative 4 na maua i le reflux o le 2 i le formic acid mo le 5 itula i se fua maualuga.Acetic acid N'-[2-(7-hydroxy-2-oxo-2 H-chromen-4-yl)-acetyl]-hydrazide (5) na maua mai i le reflux acetylation o le 2 i le acetic acid i se fua lelei.Fa'aputu 6 e maua fo'i e ala i le toe fa'afo'iina o le 2 ma le 3-(2-bromoacetyl) -4-hydroxy-2 H-chromen-2-one i le ethanol.O le tuufaatasiga 2 e tali atu i le phenyl isothiocyanate i le ethanol i le vevela o le potu e maua ai le 4-phenyl-1-(7-hydroxy-2-oxo-2 H-chromen-4-acetyl -)-thiosemicarbazide (7).
3-{2-[2-(7-hydroxy-2-oxo-2 H-chromen-4-yl)-acetyl]hydrazono}butanoate (8) ethyl ester (8), 3-{2-[2-( 7-hydroxy-2-oxo-2 H-Chromen-4-yl)-acetyl] Hydrazono} Butanoate (8), O le fua o le 48% (Filifiliga 2).O le faʻatulagaina o faʻalapotopotoga 4-8 na faʻamoemoeina e latou faʻamatalaga auʻiliʻili ma a latou IR ma le 1 H-NMR spectra.O le faʻaogaina o le infrared ona o le NH, OH ma C = O galuega faʻaalia i le 3450-3000 ma le 1728-1610cm-1, i le faasologa.O fusi faʻafefe e fesoʻotaʻi ma le i ai o isi vaega galue o loʻo i ai i le itulagi faʻamoemoeina.Ole fusi ole fusi ole 1 H-NMR o loʻo faʻaalia ai se tumutumu tasi i le itulagi 8.03-10.58ppm e fetaui ma NH ma OH protons.Vaega 4-8