Calcitonin salmon CAS 47931-85-1 Salmotonin Thyrocalcitonin
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Sebopeho:
| Lebitso le tloaelehileng | letsoai la calcitonin | Lebitso la Senyesemane | Salmon Calcitonin Acetate |
|---|---|---|---|
| Nomoro ea CAS | 47931-85-1 |
| Botenya | 1.5±0.1g/cm3 |
|---|---|
| Mokhoa oa limolek'hule | C145H240N44O48S2 |
| Boima ba molek'hule | 3431.853 |
| Boima bo nepahetseng | 3429.713379 |
| PSA | 1558.81000 |
| LogP | -12,48 |
| Litšobotsi tsa ponahalo | phofo |
| Lenane la refractive | 1.677 |
| Maemo a polokelo | E tiisitsoe, boloka ho -18 ºC |
| Botsitso | Ha ho na ho bola, ha ho na likarabelo tse kotsi tse tsejoang haeba li sebelisoa le ho bolokoa ho latela litlhaloso |
| Ho qhibiliha ha metsi | 0.05 M acetic acid: 1 mg / mL, e hlakileng, e se nang mebala |
Tšebeliso:
Calcitonin Salmon ke hormone ea polypeptide e hlahisoang ke tšoelesa ea salmon ea ultimobranchial.Ke ea lelapa la protheine e kang calcitonin 'me e ka sebelisoa ho phekola lefu la Paget la masapo, postmenopausal osteoporosis(masapo a pshatlehileng kapa a robehileng), kapa maemo a phahameng a calcium maling (hypercalcemia).E bonahala e na le liketso tse ts'oanang hantle le li-calcitonin tsa tlhaho ea mammalian, empa matla a eona ka mg a kholoanyane mme e na le nako e telele ea ts'ebetso.E sebetsa haholo-holo ka Ho thibela osteoclastic bone resorption, ho fokotsa serum calcium, le ho eketsa excretion ea renal ea phosphate, calcium, sodium magnesium le potasiamo ka ho fokotsa ho tsosolosoa ha tubular.
Ho batho, salmon calcitonin e sebetsa ho feta analog ea eona ea motho.
Calcitonin (salmon) e na le tšusumetso e ntle ho lokisoa ha masapo le ho teteana ha masapo ka lebaka la phello ea eona e thibelang ts'ebetso ea osteoclast.Phello e ntle ea salmon calcitonin kalafong ea ho robeha ha masapo a osteoporotic e boetse e bakoa ke ho khothaletsoa ha karolo ea lefufuru ea pholiso ea fracture le ho imolla bohloko.
Salmon ea Calcitonin e ka sebelisoa bakeng sa tlhahlobo ea calcitonin receptor / cAMP bakeng sa ho hlahloba boteng ba li-receptor tsa calcitonin tse hlahisoang ke lisele tsa TRAP +. Sehlahisoa se ka boela sa sebelisoa e le motsoako oa tlhahlobo bakeng sa ho ithuta hammoho le ho bapisa phello ea calcitonin gene e amanang le peptide (CGRP) le salmon calcitonin (sCT) e thibelang mucosal ea ka mpeng ho likhoto tse pepesehileng khatello ea kelello e batang + (CRS).
