Salmon ya Calcitonin CAS 47931-85-1 Salmotonin Thyrocalcitonin
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Ibiranga:
| Izina rusange | salmon calcitonin | Izina ry'icyongereza | Salmon Calcitonin Acetate |
|---|---|---|---|
| Numero ya CAS | 47931-85-1 |
| Ubucucike | 1.5 ± 0.1g / cm3 |
|---|---|
| Inzira ya molekulari | C.145H.240N.44O.48S.2 |
| Uburemere bwa molekile | 3431.853 |
| Misa nyayo | 3429.713379 |
| PSA | 1558.81000 |
| LogP | -12.48 |
| Ibiranga isura | ifu |
| Ironderero | 1.677 |
| Imiterere yo kubika | Ikidodo, ubike kuri -18 ºC |
| Igihagararo | Nta kubora, nta reaction izwi izwi iyo ikoreshejwe kandi ibitswe ukurikije ibisobanuro |
| Amazi meza | 0,05 M acide acetike: 1 mg / mL, isobanutse, idafite ibara |
Ikoreshwa:
Calcitonin Salmon ni imisemburo ya polypeptide isohoka na glande ultimobranchial gland ya salmon.Ni iy'umuryango wa protein umeze nka calcitonine kandi urashobora gukoreshwa mu kuvura indwara ya Paget yamagufwa, osteoporose ya postmenopausal (amagufwa yoroheje cyangwa yoroheje), cyangwa calcium nyinshi mumaraso (hypercalcemia).Bigaragara ko bifite ibikorwa bisa na calcitonine ikomoka ku nyamaswa z’inyamabere, ariko imbaraga zayo kuri mg nini kandi ifite igihe kirekire cyibikorwa.Ikora cyane cyane Kubuza amagufwa ya osteoclastique, kugabanya calcium ya calcium, no kongera impyiko zo mu bwoko bwa fosifate, calcium, sodium magnesium na potasiyumu mu kugabanya igituba reabsorption.
Mu bantu, salmon calcitonine ikora cyane kuruta uko abantu bagereranya.
Calcitonine (salmon) igira ingaruka nziza kuvugurura amagufwa hamwe nubucucike bwamagufwa bitewe ningaruka zayo zibuza ibikorwa bya osteoclast.Ingaruka nziza ya salmon calcitonine mukuvura amagufwa ya osteoporotique nayo iterwa no kuzamura icyiciro cya karitsiye yo gukiza kuvunika no kugabanya ububabare.
Salmon ya Calcitonine irashobora gukoreshwa muburyo bwa calcitonin reseptor / cAMP kugirango isuzume ahari reseptor ya calcitonine yagaragajwe na selile TRAP +.Ibicuruzwa birashobora kandi gukoreshwa nk'ikizamini cyo gupima kimwe no kugereranya ingaruka ziterwa na peptide ya calcitonine (CGRP) na salmon calcitonine (sCT) kuri barrière mucosal barrière mu mbeba zihura n'imbeho + yo gukumira (CRS).
