Calcitonin salmon CAS 47931-85-1 Salmotonin Thyrocalcitonin
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Hunhu:
| Common name | salmon calcitonin | Zita rechirungu | Salmon Calcitonin Acetate |
|---|---|---|---|
| CAS nhamba | 47931-85-1 |
| Density | 1.5±0.1g/cm3 |
|---|---|
| Molecular formula | C145H240N44O48S2 |
| Molecular uremu | 3431.853 |
| Misa yakarurama | 3429.713379 |
| PSA | 1558.81000 |
| LogP | -12.48 |
| Chitarisiko hunhu | upfu |
| Refractive index | 1.677 |
| Kuchengetedza mamiriro | Yakavharwa, chengetedza pa -18 ºC |
| Kugadzikana | Hapana kuora, hapana maitiro ane ngozi anozivikanwa kana akashandiswa uye akachengetwa zvinoenderana nezvinodiwa |
| Kunyungudika kwemvura | 0.05 M acetic acid: 1 mg / mL, yakajeka, isina ruvara |
Kushandisa:
Calcitonin Salmon ihomoni yepolypeptide inovanzwa neultimobranchial gland yesalmon.Iyo ndeye calcitonin-yakafanana neprotein mhuri uye inogona kushandiswa kurapa chirwere chePaget's bone, postmenopausal osteoporosis (mafupa asina kusimba kana anoputika), kana kuwanda kwe calcium muropa (hypercalcemia).Inoratidzika kunge ine zviito zvakangofanana necalcitonins yemammalian yakabva, asi simba rayo pamg yakakura uye ine nguva yakareba yekuita.Inoshanda zvakanyanya neInhibiting osteoclastic bone resorption, kuderedza serum calcium, uye kuwedzera renal excretion yephosphate, calcium, sodium magnesium uye potassium nekuderedza tubular reabsorption.
Muvanhu, salmon calcitonin inoshanda zvakanyanya kupfuura analogi yayo yemunhu.
Calcitonin (salmon) inokanganisa kugadziridza kwemapfupa uye kusimba kwefupa nekuda kwekudzivisa kwayo kuita osteoclast.Kubatsira kunobatsira kwesalmon calcitonin mukurapa osteoporotic bone fractures inokonzerwawo nekusimudzirwa kwechikamu checartilaginous chekuporesa kwekutyoka uye kubvisa marwadzo.
Calcitonin salmon inogona kushandiswa calcitonin receptor/cAMP assay yekuongorora kuvapo kwecalcitonin receptors inoratidzwa neTRAP + masero. salmon calcitonin (sCT) pagastric mucosal barriers mumakonzo akafumurwa kutonhora + kuzvidzora kushushikana (CRS).
