Tom ntej: Calcitonin Salmon CAS 47931-85-1 Salmotonin Thyrocalcitonin
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Yam ntxwv:
| Hom npe | salmon calcitonin | English npe | Salmon Calcitonin Acetate |
|---|---|---|---|
| CAS nr | 47931-85-1 |
| Qhov ntom | 1.5 ± 0.1g / cm3 |
|---|---|
| Cov mis mos molecular | C145H240N44O48S2 |
| Molecular hnyav | 3431.853 ib |
| Qhov tseeb loj | 3429.713379 ib |
| PSA | 1558.81000 Nws |
| LogP | - 12.48 Nws |
| Cov tsos mob tshwm sim | hmoov |
| Refractive Index | 1.677 ib |
| Cia tej yam kev mob | Muab kaw, khaws cia ntawm -18 ºC |
| Kev ruaj ntseg | Tsis muaj decomposition, tsis paub muaj kev phom sij yog tias siv thiab khaws cia raws li cov lus qhia tshwj xeeb |
| Dej solubility | 0.05 M acetic acid: 1 mg / mL, ntshiab, tsis muaj xim |
Kev siv:
Calcitonin Salmon yog polypeptide hormone secreted los ntawm ultimobranchial caj pas ntawm salmon.Nws belongs rau tsev neeg cov protein zoo li calcitonin thiab tuaj yeem siv los kho Paget's kab mob ntawm cov pob txha, postmenopausal osteoporosis (cov pob txha mos los yog nkig), lossis cov calcium ntau hauv cov ntshav (hypercalcemia).Nws zoo nkaus li muaj cov haujlwm tseem ceeb zoo ib yam rau cov calcitonins ntawm cov tsiaj yug tsiaj, tab sis nws cov potency ib mg yog ntau dua thiab nws muaj lub sijhawm ntev ntawm kev ua.Nws ua haujlwm feem ntau los ntawm Inhibiting osteoclastic pob txha resorption, txo cov ntshav calcium, thiab ua rau lub raum excretion ntawm phosphate, calcium, sodium magnesium thiab potassium los ntawm kev txo tubular reabsorption.
Nyob rau hauv tib neeg, salmon calcitonin yog nquag tshaj nws cov tib neeg analog.
Calcitonin (salmon) zoo cuam tshuam cov pob txha kho thiab pob txha pob txha pob txha vim nws inhibiting nyhuv ntawm osteoclast kev ua si.Cov txiaj ntsig zoo ntawm salmon calcitonin hauv kev kho cov pob txha osteoporotic pob txha kuj yog vim kev txhawb nqa ntawm cov theem cartilaginous ntawm pob txha kho thiab kho mob.
Calcitonin salmon tuaj yeem siv rau calcitonin receptor / cAMP assay rau kev ntsuam xyuas qhov muaj calcitonin receptors qhia los ntawm TRAP + cells.Cov khoom siv kuj tseem siv tau los ua ib qho kev sim tshuaj rau kev kawm nrog rau kev sib piv qhov cuam tshuam ntawm calcitonin gene ntsig txog peptide (CGRP) thiab salmon calcitonin (sCT) ntawm gastric mucosal barrier nyob rau hauv nas raug mob khaub thuas + kev nyuaj siab (CRS).
