Calcitonin salmon CAS 47931-85-1 Salmotonin Thyrocalcitonin
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Sifada:
| Magaca guud | salmon calcitonin | Magaca Ingiriisiga | Salmon Calcitonin Acetate |
|---|---|---|---|
| Lambarka CAS | 47931-85-1 |
| Cufnaanta | 1.5±0.1g/cm3 |
|---|---|
| qaacidada molecular | C145H240N44O48S2 |
| Miisaanka molecular | 3431.853 |
| Tirada saxda ah | 3429.713379 |
| PSA | 1558.81000 |
| LogP | -12.48 |
| Astaamaha muuqaalka | budo |
| Tilmaanta refractive | 1.677 |
| Xaaladaha kaydinta | Xidhan, ku kaydi -18ºC |
| Xasilooni | Ma jiro burbur, lama yaqaan fal-celin khatar ah haddii la isticmaalo oo loo kaydiyo si waafaqsan tilmaamaha |
| Biyuhu milma | 0.05 M acetic acid: 1 mg/mL, cad, aan midab lahayn |
Isticmaalka:
Calcitonin Salmon waa hoormoon polypeptide ah oo ay soo saarto qanjirka ultimobranchial ee salmon.Waxay ka tirsan tahay qoyska borotiinka u eg calcitonin waxaana loo isticmaali karaa in lagu daweeyo cudurka Paget ee lafaha, postmenopausal osteoporosis (lafo jilicsan ama jajaban), ama heerarka sare ee calcium ee dhiigga (hypercalcemia).Waxay u muuqataa inay leedahay ficilo asal ahaan la mid ah calcitonins oo asal ahaan naaslay ah, laakiin awooddeeda mgkiiba way ka weyn tahay waxayna leedahay waqti dheer oo ficil ah.Waxay u shaqeysaa inta badan iyadoo la joojinayo dib-u-soo-celinta lafaha osteoclastic, hoos u dhigista kalsiyumka serum, iyo kordhinta saxarada kelyaha ee fosfat, kalsiyum, sodium magnesium iyo potassium iyadoo hoos u dhigaysa dib-u-habaynta tuubada.
Bini'aadamka, salmon calcitonin waa ka firfircoon yahay analooga aadanaha.
Calcitonin (salmon) ayaa si togan u saameeya dib-u-qaabaynta lafaha iyo cufnaanta lafaha sababtoo ah saameynteeda joojinta dhaqdhaqaaqa osteoclast.Saamaynta faa'iidada leh ee salmon calcitonin ee daaweynta jabka lafaha laf-dhabarka ayaa sidoo kale sabab u ah horumarinta marxaladda cartilaginous ee bogsashada jabka iyo xanuunka xanuunka.
Calcitonin salmon waxaa loo isticmaali karaa calcitonin receptor / cAMP assay si loo qiimeeyo joogitaanka calcitonin reseptors ee ay muujiyeen unugyada TRAP +. Badeecada sidoo kale waxaa loo isticmaali karaa xarun tijaabo ah oo loogu talagalay barashada iyo sidoo kale isbarbardhigga saameynta calcitonin ee la xidhiidha peptide (CGRP) iyo salmon calcitonin (sCT) oo ku saabsan xannibaadda xuubka caloosha ee jiirka ee soo gaadhay hargab + cadaadiska xakamaynta (CRS).
