C-Telopeptide CAS;162929-64-8 L-Arginine L-α-glutamyl-L-lysyl-L-alanyl-L-histidyl-L-a-aspartylglycylglycyl-

C-terminal peptide (CTX), kuma aka sani da carboxy-terminal collagen crosslinking, shi ne C-terminal peptide na fibrous collagens kamar nau'in I da nau'in II.Ana amfani da shi azaman alamar halitta a cikin jini don auna juyar da kashi.Ana iya amfani da shi don taimaka wa likitoci su tantance martanin majiyyaci game da jiyya ba tare da tiyata ba, da kuma tantance haɗarin rikitarwa na majiyyaci yayin warkarwa bayan aikin tiyata.[1] Gwajin don alamomin CTX, wanda ake kira Serum CrossLaps, ya fi ƙayyadaddun ƙashi fiye da kowane gwajin da ake samu a halin yanzu.

A farkon 2000s, an lura da hanyar haɗi tsakanin amfani da bisphosphonate da lalacewar ilimin lissafi ga kashi.Ƙunƙarar hana aikin osteoclast ta hanyar bisphosphonate far na iya haifar da dakatar da jujjuyawar kashi na yau da kullum, wanda ya haifar da raunin raunin da ya faru bayan rauni (kamar tiyata na hakori), har ma da rashin warkarwa na kashi.Saboda an fi ajiye bisphosphonate a cikin ƙasusuwa tare da babban canji, matakan bisphosphonate a cikin muƙamuƙi na iya ɗauka da zaɓaɓɓu.

Tare da zuwan ƙwararrun haƙori, ana samun karuwar masu cutar haƙori da suka shafi warkar da kashi a cikin baki, kamar aikin tiyata da dasa ƙashi.Don tantance haɗarin osteonecrosis a cikin marasa lafiya da ke shan bisphosphonates, Rosen ya gabatar da CTX biomarker a cikin 2000.