Myomodulin CAS: 110570-93-9 H-Pro-Met-Ser-Met-Leu-Arg-Leu-NH2

Neuropeptide myodulin, ƙananan peptide mai aiki na zuciya (SCP) da furotin buccal suna yadu a cikin phylum mollusca kuma suna da muhimman ayyuka na jiki.Anan mun bayyana cikakken rarraba kowane nau'in peptide a cikin tsarin juyayi na tsakiya (CNS) na Lymnaea stagnalis ta hanyar amfani da dabarun immunocytochemical a hade tare da lakabin rini na neurons da aka gano ta hanyar electrophysiology.Muna ba da rahoto game da keɓewa da yanayin tsarin A Lymnaomodulin PMSMLRLamide, wanda yayi daidai da myomodulin A daga kuren teku.Myomodulin immunoreactivity yana cikin duk ganglia 11, nama mai haɗin gwiwa, da jijiyoyi na gefe.A yawancin lokuta, myomodulin immunoreactivity yana bayyana a cikin gungu na ƙananan ƙwayoyin cuta masu bayyana FMRFamide-kamar peptides, amma kuma a cikin adadi mai yawa na sauran ƙwayoyin cuta.Ƙididdigar lakabi sau biyu ya nuna immunoreactivity na myomodulin a cikin fararen interneurons na visceral da ke cikin tsarin tsarin zuciya.Scp-kamar rigakafi reactivity shima yana nan a cikin duk ganglia, kuma ƙididdigar lakabi biyu suna nuna cewa yana da alaƙa da ƙayyadaddun gungu na exons daban-daban da aka bayyana daban-daban a cikin CNS na kwayar FMRFamide a wurare da yawa.Koyaya, halayen antiserums guda biyu na SCP da aka yi amfani da su a cikin wannan binciken sun ba da shawarar cewa sun ƙetare amsawa tare da FMRFamide da n-terminal ƙaramar FmrFamide-kamar peptides.Zaɓin preadsorption ta amfani da waɗannan peptides masu amsawa sun haifar da kawar da tabo mai yawa da kuma riƙe da ingantaccen amsawar SCP na gaskiya kawai a cikin buccal da ganglia ƙafa.Immunoreactivity na furotin buccal ya iyakance ga ganglia na buccal da ƙafa.Bai dace da rarraba myomodulin ko SCP ba.Yawancin gungu na amsa rigakafi ana samun su a cikin ganglion na ƙafa.Bai dace da rarraba myomodulin ko SCP ba.Yawancin gungu na amsa rigakafi ana samun su a cikin ganglion na ƙafa.Bai dace da rarraba myomodulin ko SCP ba.Yawancin gungu na amsa rigakafi ana samun su a cikin ganglion na ƙafa.