C-Telopeptide CAS;162929-64-8 L-Arginine L-α-glutamyl-L-lysyl-L-alanyl-L-histidyl-L-α-aspartylglycylglycyl-

C-terminal peptide (CTX), izwi kandi nka carboxy-terminal collagen crosslinking, ni C-terminal peptide ya fibrous collagens nkubwoko bwa I nubwoko bwa II.Ikoreshwa nka biomarker muri serumu gupima amagufwa.Irashobora gukoreshwa mu gufasha abaganga kumenya uko umurwayi yakira imiti idakira, ndetse no gusuzuma ibyago umurwayi ashobora guhura na byo mugihe cyo gukira nyuma yo kubagwa.Ikizamini cyibimenyetso bya CTX, cyitwa Serum CrossLaps, kirasobanutse cyane kubijyanye no gufata amagufwa kurusha ikindi kizamini kiboneka ubu

Mu ntangiriro ya 2000, hagaragaye isano hagati yo gukoresha bisphosifone no kwangiza amagufwa.Kubuza cyane imikorere ya osteoclast hamwe nubuvuzi bwa bisphosifone birashobora gutuma habaho guhagarika amagufwa asanzwe, bikaviramo gukira ibikomere nyuma yo guhahamuka (nko kubaga amenyo), ndetse no guhita bidakiza amagufwa.Kuberako bisphosifone ishyirwa mumagufwa afite ibicuruzwa byinshi, urugero rwa bisphosifone mu rwasaya rushobora kuzamurwa neza.

Hamwe no gutera amenyo, umubare munini w'abarwayi b'amenyo barimo kwivuza birimo gukira amagufwa mu kanwa, nko kubaga no kubaga amagufwa.Kugirango hamenyekane ingaruka ziterwa na osteonecrosis ku barwayi bafata bisifosifone, Rosen yazanye biomarker ya CTX mu 2000