C-Telopeptide CAS;162929-64-8 L-Arginine L-α-glutamyl-L-lysyl-L-alanyl-L-histidyl-L-α-aspartylglycylglycyl-

ʻO C-terminal peptide (CTX), i ʻike ʻia ʻo carboxy-terminal collagen crosslinking, he peptide C-terminal o nā collagens fibrous e like me ke ʻano I a me ke ʻano II.Hoʻohana ʻia ia ma ke ʻano he biomarker i ka serum e ana i ka huli iwi.Hiki ke hoʻohana ʻia e kōkua i nā kauka e hoʻoholo i ka pane o ka mea maʻi i ka lāʻau lapaʻau nonsurgical, a me ka loiloi ʻana i ka pilikia o ka mea maʻi i nā pilikia i ka wā hoʻōla ma hope o ke kaʻina hana.[1] ʻO ka hoʻāʻo no nā māka CTX, i kapa ʻia ʻo Serum CrossLaps, ʻoi aku ka kikoʻī no ka resorption iwi ma mua o nā hoʻokolohua ʻē aʻe i loaʻa i kēia manawa.

I ka 2000 mua, ua ʻike ʻia kahi loulou ma waena o ka hoʻohana ʻana i ka bisphosphonate a me ka pōʻino physiological i ka iwi.ʻO ke kāohi ikaika ʻana o ka hana osteoclast e ka bisphosphonate therapy hiki ke hoʻopau i ka huli ʻana o ka iwi maʻamau, ka hopena i ka hōʻeha ʻana i ka ʻeha ma hope o ka trauma (e like me ka ʻoki niho), a me ka ʻike ʻole ʻana o ka iwi hoʻōla.Ma muli o ka waiho ʻia ʻana o ka bisphosphonate i loko o nā iwi me ka hoʻololi kiʻekiʻe, hiki ke hoʻokiʻekiʻe ʻia nā pae bisphosphonate i ka iwi ā.

Me ka hiki ʻana mai o nā implants niho, ke piʻi nei ka heluna o nā maʻi niho e mālama nei i nā lāʻau lapaʻau e pili ana i ka ho'ōla iwi ma ka waha, e like me nā implants a me nā grafts iwi.No ka loiloi i ka pilikia o ka osteonecrosis i nā poʻe maʻi e lawe ana i nā bisphosphonates, ua hoʻokomo ʻo Rosen i ka biomarker CTX ma 2000