Larazotide acetate CAS 881851-50-9
Ikopanye le 'na
Email : salesperson66@yeah.net
whatsapp: +8619832408762
wickr: fairyqf
Skype:+8619832408762
Sebopeho:
| lebitso le tloaelehileng | Larazotide Acetate | Lebitso la Senyesemane | Larazotide acetate |
|---|---|---|---|
| Nomoro ea CAS | 881851-50-9 | boima ba molek'hule | 785.88500 |
| foromo ea limolek'hule | C34H59N9O12 |
|---|
| boima bo nepahetseng | 785.42800 |
|---|---|
| PSA | 360.55000 |
| LogP | 3.73650 |
Tšebeliso:
Larazotide acetate ke lithethefatsi tse laolang mala a thata-thata, tse neng li tsejoa e le Innovate Biopharmaceuticals pele li kopana, tse ntseng li lekoa ho bakuli ba baholo ba nang le lefu la celiac tekong ea kliniki ea phase III.Peptide ena ea ketane e le 'ngoe e tsoa ho zonulin ea motho, e leng modulator e tsebahalang ea ho kenella ka thata ka har'a matekoane e phahamisitseng polelo ea lisele tsa mala ho bakuli ba nang le lefu la celiac.LA e boetse e arolelana sebopeho sa sebopeho le Vibrio cholerae zonula occludens toxin (Zot), e leng enterotoxin e senyang sebopeho sa intercellular tight junction ka actin polymerization le liphetoho tsa cytoskeletal tse fellang ka ho eketseha ha mala a mala ka pontšo ea intracellular.Le hoja LA e bontšitse tšepiso litekong tsa meriana bakeng sa bakuli ba nang le lefu la celiac, liphuputso tsa morao-rao tse sebelisang mefuta e sa tšoaneng ea likotsi tsa liphoofolo li bontša hore ho ka sebelisoa LA bakeng sa mafu a mang ka lebaka la bokhoni ba eona ba ho laola lihlopha tse thata.Tlhahlobo ena e nyane e ikemiselitse ho fana ka mohloli o felletseng oa tlhaiso-leseling ea hajoale mabapi le octapeptide ena.
