Larazotide acetate CAS 881851-50-9
Ndiuzeni:
Email : salesperson66@yeah.net
whatsapp: +8619832408762
wickr: fairyqf
Skype: +8619832408762
Khalidwe:
| dzina wamba | Larazotide Acetate | Dzina lachingerezi | Larazotide acetate |
|---|---|---|---|
| Nambala ya CAS | 881851-50-9 | kulemera kwa maselo | 785.88500 |
| mawonekedwe a molekyulu | C34H59N9O12 |
|---|
| misa yolondola | 785.42800 |
|---|---|
| PSA | 360.55000 |
| LogP | 3.73650 |
Kagwiritsidwe:
Larazotide acetate ndi intestinal tight-junction regulator drug , yomwe poyamba inkadziwika kuti Innovate Biopharmaceuticals isanagwirizane, yomwe ikuyesedwa pakali pano mwa odwala akuluakulu omwe ali ndi matenda a celiac muyeso lachipatala la gawo lachitatu.Peptide yokhala ndi unyolo umodzi imachokera ku zonulin yaumunthu, modulator yodziwika bwino ya mphumu yolimba yomwe yakweza kuwonetsa kwamatumbo am'mimba mwa odwala omwe ali ndi matenda a celiac.LA imagawananso zofananira ndi Vibrio cholerae zonula occludens toxin (Zot), yomwe ndi enterotoxin yomwe imasokoneza kaphatikizidwe kake ka intercellular kudzera mu actin polymerization ndi kusintha kwa cytoskeletal komwe kumapangitsa kuti matumbo achuluke kudzera m'mitsempha yamagazi.Ngakhale kuti LA yasonyeza lonjezo m'mayesero achipatala kwa odwala omwe ali ndi matenda a celiac, kafukufuku waposachedwapa pogwiritsa ntchito mitundu yosiyanasiyana ya kuvulala kwa nyama amasonyeza kuti angagwiritse ntchito LA chifukwa cha matenda ena chifukwa cha mphamvu yake yolamulira zopinga zolimba.Ndemanga yaying'ono iyi ikufuna kupereka gwero latsatanetsatane lazidziwitso zaposachedwa pa octapeptide iyi.
