Larazotide acetate CAS 881851-50-9
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Njirimara:
| aha nkịtị | Larazotide acetate | Aha bekee | Larazotide acetate |
|---|---|---|---|
| Nọmba CAS | 881851-50-9 | molekụla arọ | 785.88500 |
| usoro ihe omimi | C34H59N9O12 |
|---|
| ezigbo uka | 785.42800 |
|---|---|
| PSA | 360.55000 |
| LogP | 3.73650 |
Ojiji:
Larazotide acetate bụ ọgwụ na-achịkwa eriri afọ, nke a na-akpọbu Innovate Biopharmaceuticals tupu njikọta, nke a na-anwale ugbu a na ndị okenye nwere ọrịa celiac na usoro nke III.A na-enweta peptide nke otu agbụ a sitere na zonulin mmadụ, onye ama ama modulator nke nkwụsi ike nke njikọ nke na-ebuli nkwupụta anụ ahụ eriri afọ na ndị ọrịa nwere ọrịa celiac.LA na-ekerịtakwa myirịta n'ụdị ya na Vibrio cholerae zonula occludens toxin (Zot), nke bụ enterotoxin nke na-akpaghasị usoro njikọ njikọta nke intercellular site na actin polymerization na mgbanwe cytoskeletal nke na-ebute mmụba nke eriri afọ site na akara intracellular.Ọ bụ ezie na LA egosila nkwa na nnwale ụlọ ọgwụ maka ndị ọrịa na-arịa ọrịa celiac, ọmụmụ ihe na-adịbeghị anya na-eji ụdị mmerụ ahụ anụmanụ dị iche iche na-egosi enwere ike iji LA maka ọrịa ndị ọzọ n'ihi ikike ya ịhazi njikọ siri ike.Nlebanya pere mpe a bu n'obi inye nkọwa zuru oke nke ozi dị ugbu a na octapeptide a.
