Anti-botsofali Hexapeptide-11 CAS 161258-30-6 Fokotsa ponahalo ea wrinkles
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Sebopeho:
| Lebitso le tloaelehileng | Hexapeptide-11 | Lebitso la Senyesemane | Hexapeptide-11 |
|---|---|---|---|
| Nomoro ea CAS | 161258-30-6 |
| Mokhoa oa limolek'hule | C36H48N6O7 |
|---|---|
| Boima ba molek'hule | 676.80200 |
| Boima bo nepahetseng | 676.35800 |
| PSA | 201.71000 |
| LogP | 4.09300 |
Tšebeliso:
Hexapeptide-11 ke modulator e ncha ea marang-rang a proteostasis ho batho ba diploid fibroblasts.
Hexapeptide-11 e fokotsa ponahalo ea mela e metle le wrinkles, e etsa hore sena e be tlatsetso e ntle ho mefuta eohle ea tlhokomelo ea letlalo le lihlahisoa tse thibelang botsofali.E na le sete e ikhethang ea li-amino acid tse thusang ho laola maemo a collagen le ho matlafatsa letlalo la letlalo.
Ho pepeseha ha fibroblasts ho Hexapeptide-11 ho khothaletsoa lethal dose le ts'ebetso e itšetlehileng ka nako ea proteasome, autophagy, chaperones le liphatsa tsa lefutso tse amanang le antioxidant.Ho feta moo, e khothalelitse ho bokellana ha nyutlelie ho Nrf2;maemo a phahameng a polelo ea li-subunits tsa proteasomal protheine le ho eketseha ha mesebetsi ea proteasome peptidase.Tumellanong le liphuputso tsena re hlokometse hore Hexapeptide-11 e fane ka tšireletso e kholo ho li-fibroblasts khahlano le senescence ea cellular ea pele ho nako ea oxidative-stress-mediated, ha litekong tsa deformation ea letlalo la vivo lithutong tsa batho e ile ea ntlafatsa letlalo.
