Hexapeptide na-egbochi ịka nká-11 CAS 161258-30-6 Belata ọdịdị nke wrinkles.
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Njirimara:
| Aha nkịtị | Hexapeptide-11 | Aha bekee | Hexapeptide-11 |
|---|---|---|---|
| Nọmba CAS | 161258-30-6 |
| Usoro ihe omimi | C36H48N6O7 |
|---|---|
| Ibu molekụla | 676.80200 |
| Ezi uka | 676.35800 |
| PSA | 201.71000 |
| LogP | 4.09300 |
Ojiji:
Hexapeptide-11 bụ ihe ọhụrụ modulator nke netwọk proteostasis na diploid fibroblasts mmadụ.
Hexapeptide-11 na-ebelata ọdịdị nke ahịrị dị mma na wrinkles, na-eme ka nke a bụrụ mgbakwunye magburu onwe ya na ụdị nlekọta anụ ahụ na ngwaahịa mgbochi ịka nká.O nwere amino acid pụrụ iche nke na-enyere aka ịchịkwa ọkwa nke collagen na ịkwalite ngbanwe na akpụkpọ ahụ.
Ngosipụta fibroblasts na Hexapeptide-11 kwalitere dose yana ịgbalite oge dabere na proteasome, autophagy, chaperones na nzaghachi antioxidant metụtara mkpụrụ ndụ ihe nketa.Ọzọkwa, ọ kwalitere ụbara mkpokọta nuklia nke Nrf2;ọkwa ọkwa dị elu nke subunits protein proteasomal yana mmụba nke ọrụ peptidase proteasome.N'ikwekọ na nchoputa ndị a, anyị chọpụtara na Hexapeptide-11 nyere nchebe dị ukwuu na fibroblasts megide oxidative-stress-mediated temature cellular senescence, ebe na vivo nrụrụ akpụkpọ anụ na isiokwu mmadụ, ọ na-eme ka akpụkpọ ahụ dịkwuo mma.
