Anti-kuchembera Hexapeptide-11 CAS 161258-30-6 Deredza kutaridzika kwemakwinya
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Hunhu:
| Common name | Hexapeptide-11 | Zita rechirungu | Hexapeptide-11 |
|---|---|---|---|
| CAS nhamba | 161258-30-6 |
| Molecular formula | C36H48N6O7 |
|---|---|
| Molecular uremu | 676.80200 |
| Misa yakarurama | 676.35800 |
| PSA | 201.71000 |
| LogP | 4.09300 |
Kushandisa:
Hexapeptide-11 inyowani modulator yeproteostasis network mumunhu diploid fibroblasts.
Hexapeptide-11 inoderedza kutaridzika kwemitsara yakanaka uye wrinkles, zvichiita kuti izvi zvive zvakanakisa kuwedzera kune ese marudzi ekuchengetedza ganda uye anti-kuchembera zvigadzirwa.Iyo ine yakasarudzika seti yeamino acids inobatsira kushandura collagen mazinga uye kuwedzera elasticity muganda.
Kuratidzwa kwefibroblasts kuHexapeptide-11 inosimudzira dosi uye nguva-inotsamira activation yeproteasome, autophagy, chaperones uye antioxidant mhinduro dzine hukama majini.Uyezve, yakakurudzira kuwedzera kwenyukireya kuunganidza kweNrf2;yakakwirira yekutaura mazinga eproteasomal protein subunits uye yakawedzera proteasome peptidase zviitiko.Zvinoenderana nezvakawanikwa izvi takaona kuti Hexapeptide-11 yakapa dziviriro yakakosha mufibroblasts kubva kune oxidative-stress-mediated premature cellular senescence, nepo in vivo ganda deformation assays muzvidzidzo zvevanhu zvakavandudza kusimba kweganda.
