Anti-aging Hexapeptide-11 CAS 161258-30-6 Chepetsani mawonekedwe a makwinya

Kufotokozera mwachidule:

Dzina lodziwika:Hexapeptide-11

Nambala ya CAS:161258-30-6

Molecular formula:C36H48N6O7

Kulemera kwa mamolekyu:676.8

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Khalidwe:

Dzina lodziwika	Hexapeptide-11	Dzina lachingerezi	Hexapeptide-11
Nambala ya CAS	161258-30-6

Mapangidwe a maselo	C36H48N6O7
Kulemera kwa maselo	676.80200
Misa yolondola	676.35800
PSA	201.71000
LogP	4.09300

Kagwiritsidwe:

Hexapeptide-11 ndi njira yatsopano yosinthira ma proteostasis network mu diploid fibroblasts yamunthu.

Hexapeptide-11 imachepetsa maonekedwe a mizere yabwino ndi makwinya, zomwe zimapangitsa kuti izi zikhale zowonjezera pamtundu uliwonse wa chisamaliro cha khungu ndi mankhwala oletsa kukalamba.Ili ndi gulu lapadera la ma amino acid omwe amathandizira kuwongolera milingo ya kolajeni ndikuwonjezera kukhazikika pakhungu.

Kuwonetsedwa kwa ma fibroblasts ku Hexapeptide-11 kumalimbikitsa mlingo komanso kuyambitsa kwanthawi yayitali kwa proteasome, autophagy, chaperones ndi majini okhudzana ndi antioxidant mayankho.Komanso, idalimbikitsa kuwonjezeka kwa nyukiliya ya Nrf2;Mawonekedwe apamwamba a ma proteasomal protein subunits ndi kuchuluka kwa ntchito za proteasome peptidase.Mogwirizana ndi zomwe tapeza tidawona kuti Hexapeptide-11 idateteza kwambiri ma fibroblasts motsutsana ndi ma cell oxidative-stress-mediated senescence msanga, pomwe mu vivo zoyeserera zakhungu m'mitu ya anthu zidapangitsa kuti khungu likhale lolimba.