Anti-gabowga Hexapeptide-11 CAS 161258-30-6 Yaree muuqaalka laalaabyada
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Sifada:
| Magaca guud | Hexapeptide-11 | Magaca Ingiriisiga | Hexapeptide-11 |
|---|---|---|---|
| Lambarka CAS | 161258-30-6 |
| qaacidada molecular | C36H48N6O7 |
|---|---|
| Miisaanka molecular | 676.80200 |
| Tirada saxda ah | 676.35800 |
| PSA | 201.71000 |
| LogP | 4.09300 |
Isticmaalka:
Hexapeptide-11 waa habeeyaha cusub ee shabakada proteostasis ee fibroblasts diploid aadanaha.
Hexapeptide-11 waxay yaraynaysaa muuqaalka xariiqyada ganaaxa iyo laalaabyada, taas oo ka dhigaysa mid aad u fiican dhammaan noocyada daryeelka maqaarka iyo alaabada ka hortagga gabowga.Waxay leedahay qayb gaar ah oo amino acids ah oo ka caawiya inay wax ka qabato heerarka kolajka iyo kor u qaadista barti ee maqaarka.
Soo bandhigida fibroblasts ee Hexapeptide-11 qiyaasta kor loo qaaday iyo firfircoonida waqtiga ku-tiirsanaanta ee proteasome, autophagy, chaperones iyo jawaabaha antioxidant-ka ee la xiriira.Waxaa intaa dheer, waxay kor u qaadday kororka nukliyeerka Nrf2;Heerarka muujinta sare ee borotiinka borotiinka proteasomal iyo korodhka dhaqdhaqaaqa peptidase proteasome.Iyadoo la raacayo natiijooyinkaan waxaan ogaanay in Hexapeptide-11 ay siisay difaac weyn oo ku jira fibroblasts ka hortagga oksijiinta-stress-dhexdhexaadinta miyir-qabka unugyada ee dhicis ah, halka in vivo baaritaannada qallafsanaanta maqaarka ee maadooyinka bini'aadamka ay wanaajisay maqaarka maqaarka.
