Anti-aging Hexapeptide-11 CAS 161258-30-6 Reduce the appearance of wrinkles
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Characteristic:
| Common name | Hexapeptide-11 | English name | Hexapeptide-11 |
|---|---|---|---|
| CAS number | 161258-30-6 |
| Molecular formula | C 36 H 48 N 6 O 7 |
|---|---|
| Molecular weight | 676.80200 |
| Accurate mass | 676.35800 |
| PSA | 201.71000 |
| LogP | 4.09300 |
Usage:
Hexapeptide-11 is a novel modulator of the proteostasis network in human diploid fibroblasts.
Hexapeptide-11 reduces the appearance of fine lines and wrinkles, making this an excellent addition to all kinds of skin care and anti-aging products. It has a unique set of amino acids that help to manipulate collagen levels and boost elasticity in the skin.
Exposure of fibroblasts to Hexapeptide-11 promoted dose and time-dependent activation of proteasome, autophagy, chaperones and antioxidant responses related genes. Moreover, it promoted increased nuclear accumulation of Nrf2; higher expression levels of proteasomal protein subunits and increased proteasome peptidase activities. In line with these findings we noted that Hexapeptide-11 conferred significant protection in fibroblasts against oxidative-stress-mediated premature cellular senescence, while at in vivo skin deformation assays in human subjects it improved skin elasticity.
