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Inhibitor GW0742 CAS 317318-84-6 White powder

short description:


  • Common name: GW0742
  • CAS No.: 317318-84-6
  • Aliase: 2-(4-(2-(3-fluoro-4-(trifluoromethyl)phenyl)-4-methylthiazol-5-yl)methyl)thio)-2-methylphenoxy)acetic acid
  • Appearance: White powder
  • Molecular Formula: C21H17F4NO3S2
  • Molecular Weight: 471.488
  • Melting point: 134.5-135.5 °C
  • Boiling point: 591.5±60.0 °C at 760 mmHg
  • Brands: Zhanshun
  • Packaging: 1g-25kg/bag/bottles according to the customers requirements
  • Delivery Time: We will send the goods when we received the money
  • Express: DHL,UPS,FedEx,Postal and so on.(Ps:can according customers requirements)
  • Payment method: Bank transfer,Bitcoin,Western Union and so on
  • Product Detail

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    Usage

    Andarine (S-4) is the arylpropionamide-derived compound [S-3-(4-acetylamino-phenoxy)-2-hydroxy-2-methyl-N-(4-nitro-3-trifluoromethyl-phenyl)-propionamide] first described by Yin et al. to be a selective androgen receptor modulator (SARM). Andarine (S-4) was shown by in vitro and in vivo studies to be an effective anabolic agonist, without side-effects often associated with anabolic-androgenic steroids, relating principally to substrate affinity for 5α-reductase to produce DHT in the prostate.
    The pharmacological activity of andarine suggest the great potential of andarine in the development of the clinically available SARMs, which offers unique therapeutic advantages over their steroidal counterparts and an exciting opportunity to differentially regulate the androgen effects in various target tissues, thus minimizing the interference to normal. Thus, andarine has promising in advanced clinical trials that aim to treat age-related maladies and to counteract symptoms of severe diseases such as sarcopenia and cancer cachexia.
    Andarine is a selective nonsteroidal androgen receptor (AR) agonist with Ki of 4 nM. Andarine exhibits potent and efficacious anabolic activity and results in dose-dependent stimulation of growth in prostate, seminal vesicles, respectively. Andarine has potential antiosteoporotic properties.
    Andarine (formerly known as GTx-007; S-4; GTx007; S4) is an orally bioactive and selective non-steroidal androgen receptor (AR) agonist, specifically a selective androgen receptor modulator (SARM), that has potential usefulness in muscle wasting and osteoporosis. It activates AR with a Ki of 4 nM and is tissue-selective for anabolic organs. Andarine is being investigated for treating conditions such as muscle wasting, osteoporosis and benign prostatic hypertrophy. In an animal model of benign prostatic hypertrophy, andarine was shown to reduce prostate weight with similar efficacy to finasteride, but without producing any reduction in muscle mass or anti-androgenic side effects.

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    Sarm S4 Andarine Yellow powder
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    Specifications

    common name

    SARM S4

    English name

    Andarine

    CAS number

    401900-40-1

    molecular weight

    441.358

    density

    1.5±0.1 g/cm3

    boiling point

    698.7±55.0 °C at 760 mmHg

    molecular formula

    C 19 H 18 F 3 N 3 O 6

    melting point

    70-74ºC

    PSA

    133.48000

    Flash point

    376.4±31.5 °C

    LogP

    4.01

    vapor pressure

    0.0±2.3 mmHg at 25°C

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