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Inhibitor GW0742 CAS 317318-84-6 Funfun lulú

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  • Orukọ ti o wọpọ:GW0742
  • CAS No.:317318-84-6
  • Oruko:2- (4- (2- (3-fluoro-4- (trifluoromethyl) phenyl) -4-methylthiazol-5-yl) methyl) thio) -2-methylphenoxy) acetic acid
  • Ìfarahàn:Iyẹfun funfun
  • Fọọmu Molecular:C21H17F4NO3S2
  • Ìwọ̀n Molikula:471.488
  • Ibi yo:134,5-135,5 °C
  • Oju ibi farabale:591.5± 60.0 °C ni 760 mmHg
  • Awọn burandi:Zhanshun
  • Iṣakojọpọ:1g-25kg / apo / igo ni ibamu si awọn ibeere onibara
  • Akoko Ifijiṣẹ:A yoo fi ọja ranṣẹ nigbati a ba gba owo naa
  • KIAKIA:DHL, UPS, FedEx, Ifiweranṣẹ ati bẹbẹ lọ.(Ps: le ni ibamu si awọn ibeere alabara)
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    Lilo

    Andarine (S-4) jẹ ohun elo arylpropionamide-ti ari [S-3- (4-acetylamino-phenoxy) -2-hydroxy-2-methyl-N- (4-nitro-3-trifluoromethyl-phenyl) -propionamide] akọkọ. ṣàpèjúwe nipasẹ Yin et al.lati jẹ oluyipada olugba androgen ti o yan (SARM).Andarine (S-4) ni a fihan nipasẹ in vitro ati awọn iwadii vivo lati jẹ agonist anabolic ti o munadoko, laisi awọn ipa ẹgbẹ nigbagbogbo ni nkan ṣe pẹlu awọn sitẹriọdu anabolic-androgenic, ti o jọmọ ni akọkọ si isunmọ sobusitireti fun 5a-reductase lati ṣe agbejade DHT ninu pirositeti.
    Iṣẹ iṣe elegbogi ti andarine daba agbara nla ti andarine ni idagbasoke ti awọn SARM ti o wa ni ile-iwosan, eyiti o funni ni awọn anfani itọju ailera alailẹgbẹ lori awọn ẹlẹgbẹ sitẹriọdu wọn ati aye moriwu lati ṣe iyatọ awọn ipa androgen ni awọn oriṣiriṣi awọn ara ibi-afẹde, nitorinaa dinku kikọlu si deede. .Nitorinaa, andarine ti ni ileri ni awọn idanwo ile-iwosan ti ilọsiwaju ti o ni ifọkansi lati tọju awọn aarun ti o ni ibatan ọjọ-ori ati lati koju awọn aami aiṣan ti awọn arun ti o lagbara bi sarcopenia ati cachexia akàn.
    Andarine jẹ agonist ti kii ṣe sitẹriọdu androgen receptor (AR) yiyan pẹlu Ki ti 4 nM.Andarine ṣe afihan iṣẹ ṣiṣe anabolic ti o lagbara ati imunadoko ati awọn abajade ni idasi-igbẹkẹle iwọn lilo ti idagbasoke ni pirositeti, awọn vesicles seminal, lẹsẹsẹ.Andarine ni awọn ohun-ini antiosteoporotic ti o pọju.
    Andarine (eyiti a mọ tẹlẹ bi GTx-007; S-4; GTx007; S4) jẹ bioactive orally ati yiyan ti kii-sitẹriọdu androgen receptor (AR) agonist, pataki kan yiyan androgen receptor modulator (SARM), ti o ni anfani ti o pọju ninu isonu iṣan. ati osteoporosis.O mu AR ṣiṣẹ pẹlu Ki ti 4 nM ati pe o jẹ yiyan-ara fun awọn ẹya ara anabolic.A n ṣewadii Andarine fun itọju awọn ipo bii isonu iṣan, osteoporosis ati hypertrophy prostatic alaiṣe.Ninu awoṣe ẹranko ti hypertrophy prostatic ti ko dara, a fihan andarine lati dinku iwuwo pirositeti pẹlu ipa ti o jọra si finasteride, ṣugbọn laisi iṣelọpọ eyikeyi idinku ninu ibi-iṣan iṣan tabi awọn ipa ẹgbẹ anti-androgenic.

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    Sarm S4 Andarine Yellow lulú
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    Awọn pato

    wọpọ orukọ

    SARM S4

    English orukọ

    Andarine

    nọmba CAS

    401900-40-1

    iwuwo molikula

    441.358

    iwuwo

    1,5 ± 0,1 g / cm3

    farabale ojuami

    698.7± 55.0 °C ni 760 mmHg

    molikula agbekalẹ

    C 19 H 18 F 3 N 3 O 6

    yo ojuami

    70-74ºC

    PSA

    133.48000

    oju filaṣi

    376,4 ± 31,5 °C

    LogP

    4.01

    oru titẹ

    0.0±2.3 mmHg ni 25°C

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