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Inhibitor GW0742 CAS 317318-84-6 Phofo e tšoeu

tlhaloso e khuts'oane:


  • Lebitso le tloaelehileng:GW0742
  • Nomoro ea CAS:317318-84-6
  • Aliase:2-(4-(2-(3-fluoro-4-(trifluoromethyl)phenyl)-4-methylthiazol-5-yl)methyl)thio)-2-methylphenoxy)acetic acid
  • Ponahalo:Phofo e tšoeu
  • Foromo ea molek'hule:C21H17F4NO3S2
  • Boima ba Molek'hule:471.488
  • Sebaka sa ho qhibiliha:134.5-135.5 °C
  • Sebaka se belang:591.5±60.0 °C ho 760 mmHg
  • Mefuta:Zhanshun
  • Sephutheloana:1g-25kg / mokotla / libotlolo ho latela litlhoko tsa bareki
  • Nako ea thomello:Re tla romela thepa ha re fumana chelete
  • Express:DHL,UPS,FedEx,Postal joalo-joalo.(Ps: na ho latela litlhoko tsa bareki)
  • Mokhoa oa tefo:Phetiso ea banka, Bitcoin, Western Union joalo-joalo
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    Tšebeliso

    Andarine (S-4) ke motsoako o tsoang ho arylpropionamide [S-3-(4-acetylamino-phenoxy)-2-hydroxy-2-methyl-N-(4-nitro-3-trifluoromethyl-phenyl) -propionamide] pele e hlalositsoe ke Yin et al.ho ba modulator ea androgen receptor (SARM) e khethiloeng.Andarine (S-4) e bontšitsoe ka lithuto tsa in vitro le in vivo hore e be agonist e sebetsang ea anabolic, ntle le litla-morao hangata tse amanang le anabolic-androgenic steroids, tse amanang haholo-holo le substrate affinity bakeng sa 5α-reductase ho hlahisa DHT ho prostate.
    Mosebetsi oa pharmacological oa andarine o fana ka maikutlo a bokhoni bo boholo ba andarine ho nts'etsopele ea li-SARM tse fumanehang tleliniking, e fanang ka melemo e ikhethang ea phekolo ho feta balekane ba bona ba steroidal le monyetla o monate oa ho laola ka tsela e fapaneng liphello tsa androgen meleng e fapaneng ea sepheo, kahoo ho fokotsa ho kena-kenana le maemo a tloaelehileng. .Kahoo, andarine e na le ts'episo ea liteko tse tsoetseng pele tsa kliniki tse ikemiselitseng ho phekola maloetse a amanang le lilemo le ho loantša matšoao a mafu a matla a kang sarcopenia le kankere ea cachexia.
    Andarine ke agonist ea khetho ea nonsteroidal androgen receptor (AR) e nang le Ki ea 4 nM.Andarine e bonts'a ts'ebetso ea anabolic e matla le e sebetsang 'me e fella ka ts'usumetso e itšetlehileng ka tekanyo ea kholo ea prostate, seminal vesicles, ka ho latellana.Andarine e na le matla a antiosteoporotic.
    Andarine (eo pele e neng e tsejoa e le GTx-007; S-4; GTx007; S4) ke agonist ea molomo ea bioactive le e khethollang e seng ea steroidal androgen receptor (AR), haholo-holo e khethollang androgen receptor modulator (SARM), e nang le thuso e ka bang molemo ho senya mesifa. le lefu la ho fokola ha masapo.E kenya tšebetsong AR ka Ki ea 4 nM mme e khetha lithane bakeng sa litho tsa anabolic.Andarine e ntse e batlisisoa bakeng sa ho phekola maemo a kang ho senyeha ha mesifa, lefu la ho fokola ha masapo le benign prostatic hypertrophy.Ka mohlala oa phoofolo ea benign prostatic hypertrophy, andarine e ile ea bontšoa ho fokotsa boima ba prostate ka katleho e tšoanang le finasteride, empa ntle le ho hlahisa phokotso leha e le efe ea mesifa ea mesifa kapa litla-morao tse khahlanong le androgenic.

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    Sarm S4 Andarine Yellow phofo
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    Litlhaloso

    lebitso le tloaelehileng

    SARM S4

    Lebitso la Senyesemane

    Andarine

    Nomoro ea CAS

    401900-40-1

    boima ba molek'hule

    441.358

    tekano

    1.5±0.1 g/cm3

    ntlha e belang

    698.7±55.0 °C ho 760 mmHg

    foromo ea limolek'hule

    C 19 H 18 F 3 N 3 O 6

    ntlha e qhibidihang

    70-74ºC

    PSA

    133.48000

    flash point

    376.4±31.5 °C

    LogP

    4.01

    khatello ea mouoane

    0.0±2.3 mmHg ho 25°C

    Ngola molaetsa wa hao mona mme o re romele wona