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mankhwala

Inhibitor GW0742 CAS 317318-84-6 ufa woyera

Kufotokozera mwachidule:


  • Dzina lodziwika:GW0742
  • Nambala ya CAS:317318-84-6
  • Chidziwitso:2-(4-(2-(3-fluoro-4-(trifluoromethyl)phenyl)-4-methylthiazol-5-yl)methyl)thio)-2-methylphenoxy)acetic acid
  • Maonekedwe:White ufa
  • Molecular formula:Chithunzi cha C21H17F4NO3S2
  • Kulemera kwa Molecular:471.488
  • Malo osungunuka:134.5-135.5 °C
  • Malo otentha:591.5±60.0 °C pa 760 mmHg
  • Mitundu:Zhanshun
  • Kuyika:1g-25kg / thumba / mabotolo malinga ndi zofuna za makasitomala
  • Nthawi yoperekera:Tidzatumiza katunduyo tikalandira ndalamazo
  • Express:DHL, UPS, FedEx, Postal ndi zina zotero. (Ps: akhoza malinga makasitomala amafuna)
  • Njira yolipirira:Kusintha kwa banki, Bitcoin, Western Union ndi zina zotero
  • Tsatanetsatane wa Zamalonda

    Zolemba Zamalonda

    Ndiuzeni

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    Kugwiritsa ntchito

    Andarine (S-4) ndi mankhwala opangidwa ndi arylpropionamide [S-3-(4-acetylamino-phenoxy)-2-hydroxy-2-methyl-N-(4-nitro-3-trifluoromethyl-phenyl)-propionamide] poyamba yofotokozedwa ndi Yin et al.kukhala wosankha androgen receptor modulator (SARM).Andarine (S-4) inasonyezedwa ndi maphunziro a mu vitro ndi mu vivo kuti ndi anabolic agonist ogwira ntchito, opanda zotsatira zomwe nthawi zambiri zimagwirizanitsidwa ndi anabolic-androgenic steroids, zokhudzana makamaka ndi gawo logwirizana la 5α-reductase kuti apange DHT mu prostate.
    Ntchito ya pharmacological ya andarine imasonyeza kuthekera kwakukulu kwa andarine pakupanga ma SARM omwe amapezeka kuchipatala, omwe amapereka ubwino wapadera wochiritsira kuposa anzawo a steroidal komanso mwayi wosangalatsa woyendetsa mosiyanasiyana zotsatira za androgen m'magulu osiyanasiyana omwe akutsata, motero kuchepetsa kusokoneza kwachibadwa. .Choncho, andarine akulonjeza mu mayesero apamwamba azachipatala omwe cholinga chake ndi kuchiza matenda okhudzana ndi ukalamba komanso kuthana ndi zizindikiro za matenda aakulu monga sarcopenia ndi cachexia ya khansa.
    Andarine ndi wosankha nonsteroidal androgen receptor (AR) agonist ndi Ki wa 4 nM.Andarine amawonetsa ntchito za anabolic zamphamvu komanso zogwira mtima ndipo zimabweretsa kukondoweza kotengera kukula kwa prostate, ma seminal vesicles, motsatana.Andarine ali ndi mphamvu ya antiosteoporotic.
    Andarine (omwe kale ankadziwika kuti GTx-007; S-4; GTx007; S4) ndi agonist yapakamwa komanso yosasankha yopanda steroidal androgen receptor (AR), makamaka yosankha androgen receptor modulator (SARM), yomwe imakhala yothandiza pakuwonongeka kwa minofu. ndi osteoporosis.Imayambitsa AR ndi Ki ya 4 nM ndipo imasankha minofu ya ziwalo za anabolic.Andarine akufufuzidwa pofuna kuchiza matenda monga kuwonongeka kwa minofu, osteoporosis ndi benign prostatic hypertrophy.Mu chitsanzo cha nyama cha benign prostatic hypertrophy, andarine inasonyezedwa kuti imachepetsa kulemera kwa prostate ndi mphamvu yofanana ndi finasteride, koma popanda kutulutsa kuchepa kwa minofu kapena zotsutsana ndi androgenic.

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    Sarm S4 Andarine Yellow powder
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    Zofotokozera

    dzina wamba

    Mtengo wa SARM S4

    Dzina lachingerezi

    Andarine

    Nambala ya CAS

    401900-40-1

    kulemera kwa maselo

    441.358

    kachulukidwe

    1.5±0.1g/cm3

    kuwira

    698.7±55.0 °C pa 760 mmHg

    mawonekedwe a molekyulu

    C 19 H 18 F 3 N 3 O 6

    malo osungunuka

    70-74ºC

    PSA

    133.48000

    pophulikira

    376.4±31.5 °C

    LogP

    4.01

    kuthamanga kwa nthunzi

    0.0±2.3 mmHg pa 25°C

    Lembani uthenga wanu apa ndikutumiza kwa ife