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Inhibitor GW0742 CAS 317318-84-6 Umgubo omhlophe

inkcazelo emfutshane:


  • Igama eliqhelekileyo:GW0742
  • Inombolo yeCAS:317318-84-6
  • Isibizo:2-(4-(2-(3-fluoro-4-(trifluoromethyl)phenyl)-4-methylthiazol-5-yl)methyl)thio)-2-methylphenoxy)acetic acid
  • Imbonakalo:Umgubo omhlophe
  • Ifomula yeemolekyuli:I-C21H17F4NO3S2
  • Ubunzima beMolekyuli:471.488
  • Indawo yokunyibilika:134.5-135.5 °C
  • Indawo yokubilisa:591.5±60.0 °C kwi-760 mmHg
  • Iimpawu:Zhanshun
  • Ukupakishwa:1g-25kg/ingxowa/iibhotile ngokweemfuno zabathengi
  • Ixesha lokuzisa:Siza kuthumela iimpahla xa sifumene imali
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  • Uhlobo lokuhlawula:Ukudluliselwa kweBhanki, iBitcoin, iWestern Union njalo njalo
  • Iinkcukacha zeMveliso

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    Email : salesperson66@yeah.net

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    Skype: +8619832408762

    Ukusetyenziswa

    I-Andarine (S-4) yi-arylpropionamide-derived compound [S-3-(4-acetylamino-phenoxy)-2-hydroxy-2-methyl-N-(4-nitro-3-trifluoromethyl-phenyl)-propionamide] kuqala ichazwe nguYin et al.ukuba ibe yimodyuli ekhethiweyo ye-androgen receptor (SARM).I-Andarine (S-4) iboniswe yi-in vitro kunye nezifundo ze-vivo ukuba ibe yi-agonist esebenzayo ye-anabolic, ngaphandle kwemiphumo emibi ehlala ihambelana ne-anabolic-androgenic steroids, ehambelana ngokuyintloko ne-substrate affinity ye-5α-reductase ukuvelisa i-DHT kwi-prostate.
    Umsebenzi we-pharmacological we-atarine ucebisa amandla amakhulu e-andarine ekuphuhliseni ii-SARM ezifumanekayo zonyango, ezibonelela ngeenzuzo ezizodwa zonyango ngaphezu kwabalingane babo be-steroidal kunye nethuba elimnandi lokulawula ngokwahlukileyo iziphumo ze-androgen kwiintlobo ezahlukeneyo zezicubu ekujoliswe kuzo, ngoko ke ukunciphisa ukuphazamiseka kokuqhelekileyo. .Ke, i-atarine inesithembiso kwizilingo eziphambili zeklinikhi ezijolise ekuphatheni izifo ezinxulumene neminyaka kunye nokuchasana neempawu zezifo ezinzima ezifana ne-sarcopenia kunye ne-cachexia yomhlaza.
    I-Andarine yinto ekhethiweyo ekhethiweyo ye-androgen receptor (AR) kunye ne-Ki ye-4 nM.I-Andarine ibonisa umsebenzi we-anabolic onamandla kwaye osebenzayo kwaye ukhokelela ekukhuthazeni okuxhomekeke kwithamo lokukhula kwi-prostate, i-seminal vesicles, ngokulandelanayo.I-Andarine ineempawu ezinokuthi zibe ne-antiosteoporotic.
    I-Andarine (eyayibizwa ngokuba yi-GTx-007; S-4; GTx007; S4) yi-agonist yomlomo kunye ne-non-steroidal androgen receptor (AR), ngokukodwa i-androgen receptor modulator (SARM), enokuba luncedo ekuchithekeni kwemisipha. kunye ne-osteoporosis.Ivula i-AR nge-Ki ye-4 nM kwaye ikhethe izicubu kumalungu e-anabolic.I-Andarine iphandwa ukunyanga iimeko ezinjengokonakala kwezihlunu, i-osteoporosis kunye ne-benign prostatic hypertrophy.Kwimodeli yezilwanyana ze-benign prostatic hypertrophy, i-andarine yaboniswa ukunciphisa ubunzima be-prostate kunye nokusebenza okufanayo kwi-finasteride, kodwa ngaphandle kokuvelisa nayiphi na ukunciphisa ubunzima be-muscle okanye i-anti-androgenic side effects.

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    Iinkcukacha

    igama eliqhelekileyo

    I-SARM S4

    Igama lesiNgesi

    IAndarine

    Inombolo yeCAS

    401900-40-1

    ubunzima bemolekyuli

    441.358

    ukuxinana

    1.5±0.1 g/cm3

    indawo ebilayo

    698.7±55.0 °C kwi-760 mmHg

    ifomula yemolekyuli

    C 19 H 18 F 3 N 3 O 6

    Indawo yokunyibilika

    70-74ºC

    PSA

    133.48000

    Indawo yokuflasha

    376.4±31.5 °C

    LogP

    4.01

    uxinzelelo lomphunga

    0.0±2.3 mmHg ku-25°C

    Bhala umyalezo wakho apha kwaye uwuthumele kuthi