CAS 52232-67-4 Teriparatide acetate Activator Teriparatide
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Sifada:
| Magaca guud | Teriparatide Acetate | Magaca Ingiriisiga | pTH (1-34) (aadmiga) cusbada acetate |
|---|---|---|---|
| Lambarka CAS | 52232-67-4 |
| qaacidada molecular | C181H291N55O51S2 |
|---|---|
| Miisaanka molecular | 4177.77000 |
| Astaamaha muuqaalka | budo |
| Xaaladaha kaydinta | Daboolka, ku kaydi -20ºC |
| Xasilooni | Ma jiro burbur, lama yaqaan fal-celin khatar ah haddii la isticmaalo oo loo kaydiyo si waafaqsan tilmaamaha |
Isticmaalka:
Teriparatide waa firfircoone PHT ah oo kicisa soosaarka monophosphate meertada G-protein ee la xidhiidha.
Teriparatide waxaa sidoo kale loo yaqaanaa hormoonka parathyroid-ka ee bini'aadamka (1-34) waxayna muujisaa saameynta anabolic ee lafaha.Teriparatide waa daawada ka hortagga lafo-jileeca taasoo kiliinikada loo isticmaalo in lagu daweeyo lafo-beelka;ma soo bandhigto faa'iido anti-resorptive, laakiin waxay kicisaa samaynta lafaha waxayna kordhisaa xoogga lafaha.Teriparatide waxay kicisaa soo-dhoweeyaha PTH1.Goobaha kiliinikada, teriparatide waxay hoos u dhigtaa jabka cusub iyo xanuunka dhabarka waxayna kordhisaa cufnaanta macdanta lafaha lumbar.Unugyada dhuuxa lafta jiirka, teriparatide waxay hagaajisaa muujinta osterix iyo Runx2;moodooyinka xayawaanka ee lammaane ah, xaruntani waxay kordhisaa korriinka osteoblastiga waxayna wanaajisaa bogsashada jabka.
