CAS 52232-67-4 Teriparatide acetate Activator Teriparatide

Kufotokozera mwachidule:

Dzina lodziwika:Teriparatide acetate

Nambala ya CAS:52232-67-4

Molecular formula:Mtengo wa C172H278N52O47S2

Kulemera kwa mamolekyu:3890.49792

Malo osungunuka:>205oC (Dec.)

Phukusi:Botolo, Chikwama, Katoni, Drum

Nthawi yoperekera:3 masiku chiphaso cha malipiro

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Khalidwe:

Dzina lodziwika	Teriparatide Acetate	Dzina lachingerezi	pTH (1-34) (munthu) mchere wa acetate
Nambala ya CAS	52232-67-4

Molecular formula	C181H291N55O51S2
Kulemera kwa maselo	4177.77000
Mawonekedwe ake	ufa
Zosungirako	Osindikizidwa, sungani pa -20 ºC
Kukhazikika	Palibe kuwola, palibe zowopsa zomwe zimadziwika ngati zitagwiritsidwa ntchito ndikusungidwa molingana ndi zomwe mukufuna

Kagwiritsidwe:

Teriparatide ndi PHT activator yomwe imapangitsa kuti G-protein cyclic monophosphate ipangidwe.

Teripatide imadziwikanso kuti recombinant human parathyroid hormone (1-34) ndipo imawonetsa zotsatira za anabolic pafupa.Teriparatide ndi mankhwala odana ndi osteoporotic omwe amagwiritsidwa ntchito pochiza matenda osteoporosis;sichiwonetsa phindu la anti-resorptive, koma imapangitsa kuti mafupa apangidwe komanso amawonjezera mphamvu ya mafupa.Teriparatide imayendetsa cholandilira cha PTH1.M'malo azachipatala, teriparatide imachepetsa kuphulika kwatsopano ndi ululu wammbuyo ndikuwonjezera kuchulukira kwa fupa la msana.M'maselo a mafupa a mbewa, teriparatide imayang'anira kufotokoza kwa osterix ndi Runx2;mu zitsanzo za nyama zophatikizika, mankhwalawa amawonjezera kusasitsa kwa osteoblast ndikuwongolera machiritso a fracture.