Tom ntej: CAS 52232-67-4 Teriparatide acetate Activator Teriparatide
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Yam ntxwv:
| Hom npe | Teriparatide Acetate | English npe | pTH (1-34) (tib neeg) acetate ntsev |
|---|---|---|---|
| CAS nr | 52232-67-4 |
| Cov mis mos molecular | C181H291N55O51S2 |
|---|---|
| Molecular hnyav | 4177.000 Nws |
| Cov tsos mob tshwm sim | hmoov |
| Cia tej yam kev mob | Muab kaw, khaws cia ntawm -20 ºC |
| Kev ruaj ntseg | Tsis muaj decomposition, tsis paub muaj kev phom sij yog tias siv thiab khaws cia raws li cov lus qhia tshwj xeeb |
Kev siv:
Teriparatide yog PHT activator uas txhawb kev tsim cov G-protein cyclic monophosphate.
Teriparatide tseem hu ua recombinant human parathyroid hormone (1-34) thiab nws nthuav tawm cov teebmeem anabolic ntawm pob txha.Teriparatide yog ib qho tshuaj tiv thaiv osteoporotic uas yog siv los kho cov pob txha;Nws tsis muaj txiaj ntsig los tiv thaiv resorptive, tab sis txhawb kev tsim cov pob txha thiab ua kom cov pob txha muaj zog.Teriparatide activates PTH1 receptor.Hauv cov chaw kho mob, teriparatide txo qis qhov tshwm sim ntawm pob txha tshiab thiab mob nraub qaum thiab ua rau cov pob txha pob txha pob txha muaj zog ntxiv.Hauv nas pob txha pob txha stromal hlwb, teriparatide upregulates qhia ntawm osterix thiab Runx2;nyob rau hauv cov tsiaj ua qauv ua ke, qhov sib xyaw no ua rau osteoblast maturation thiab txhim kho pob txha kho.
