CAS 52232-67-4 Teriparatide acetate mea hoʻoulu Teriparatide
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ʻano:
| inoa maʻamau | Teriparatide Acetate | inoa Pelekane | pTH (1-34) (kanaka) acetate paʻakai |
|---|---|---|---|
| Helu CAS | 52232-67-4 |
| ʻAno molekala | C181H291N55O51S2 |
|---|---|
| Kaumaha molekula | 4177.77000 |
| Nā hiʻohiʻona hiʻohiʻona | pauda |
| Nā kūlana mālama | Hoʻopaʻa ʻia, mālama ma -20 ºC |
| Paʻa | ʻAʻohe decomposition, ʻaʻohe hopena ʻino i ʻike ʻia inā hoʻohana a mālama ʻia e like me nā kikoʻī |
Hoʻohana:
ʻO Teriparatide kahi mea hana PHT e hoʻoulu i ka hana G-protein cyclic monophosphate e pili ana.
ʻIke ʻia ʻo Teriparatide he hormone parathyroid kanaka recombinant (1-34) a hōʻike ia i nā hopena anabolic ma ka iwi.ʻO Teriparatide kahi lāʻau anti-osteoporotic i hoʻohana ʻia e mālama i ka osteoporosis;ʻAʻole ia e hōʻike i ka pōmaikaʻi anti-resorptive, akā hoʻoulu i ka hana iwi a hoʻonui i ka ikaika o ka iwi.Hoʻoulu ʻo Teriparatide i ka PTH1 receptor.Ma nā hoʻonohonoho lapaʻau, hoʻemi ka teriparatide i ka hōʻeha hou ʻana a me ka ʻeha hope a hoʻonui i ka nui o ka mineral iwi spinal lumbar.I loko o ka iwi ʻiole stromal cell, teriparatide upregulates hōʻike osterix a me Runx2;i nā hoʻohālike holoholona i hui pū ʻia, hoʻonui kēia pūhui i ka maturation osteoblast a hoʻomaikaʻi i ka hoʻōla ʻana i ka haki.
