CAS 52232-67-4 Teriparatide acetate Activator Teriparatide
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uiga:
| Igoa masani | Teriparatide Acetate | igoa faaperetania | pTH (1-34) (tagata) masima acetate |
|---|---|---|---|
| Numera CAS | 52232-67-4 |
| fua mole | C181H291N55O51S2 |
|---|---|
| mamafa mole | 4177.77000 |
| Uiga foliga | pauta |
| Tulaga teuina | Fa'amaufa'ailoga, teu i le -20ºC |
| Maumau | Leai se pala, leai ni fa'alavelave mata'utia e iloa pe a fa'aoga ma teuina e tusa ai ma fa'amatalaga |
Fa'aoga:
Teriparatide o se PHT activator lea e faaosofia ai le gaosiga o le G-protein cyclic monophosphate.
Teriparatide e lauiloa foi o le recombinant human parathyroid hormone (1-34) ma e faʻaalia ai aafiaga anabolic i ponaivi.Teriparatide o se vailaʻau anti-osteoporotic lea e faʻaaogaina ile falemaʻi e togafitia ai le osteoporosis;e le fa'aalia ai le aoga o le anti-resorptive, ae fa'aosofia le fa'atupuina o ponaivi ma fa'ateleina le malosi o ponaivi.Teriparatide e faʻagaoioia le PTH1 receptor.I totonu o falemaʻi, o le teriparatide e faʻaitiitia ai le gau fou ma le tiga i tua ma faʻateleina le tele o minerale o ponaivi o le lumbar.I totonu o sela stromal ga'o ponaivi isumu, teriparatide upregulates faailoaga o osterix ma Runx2;i faʻataʻitaʻiga manu faʻapipiʻi, o lenei mea faʻapipiʻi e faʻateleina ai le matua o le osteoblast ma faʻaleleia le faʻamalologa gau.
