Ibikoresho bya chimique Anesthetics imiti ifasha CAS 59-46-1 PROCAINE
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Amakuru Yibanze
Ibisobanuro
Procaine ni anesthetic yaho ifite imikorere ya para-amino.Gukangurira cyane cyane imyuga, ubuvuzi bw'amenyo n'amatungo.
Ibikoresho bya Shimi
Umunyu wa hydrochloride ya 2- (diethylamino) Ethyl p-aminobenzoate (C13H21ClN2O2 cyangwa N2C6H4COOCH2CH2NH (C2H5) 2HCl) bakunze kwita procaine.Nubwo ester ya PABA idashonga mumazi, umunyu wa hydrochloride ushonga cyane mumazi.
Gukoresha
1.Procaine (Novocain) ikoreshwa cyane muburyo bwo kuvura amenyo cyangwa ubuvuzi busaba anesthesia yinjira, guhagarika periferique, cyangwa umugongo.
2.ibuza umuyoboro wa sodium
3. Procaine numuyoboro wa sodiumi uhagarika kandi ukabuza inzira zitandukanye.
Ikoreshwa
Gukoresha IvuriroProcaine yihuta cyane muri plasma na cholinesterase no mu mwijima ikoresheje ester hydrolysisby pseudocholinesterase.Muri vitroelimination igice cyubuzima ni amasegonda 60.Ikintu cyose kigabanya ubukana bwa cholinesterase gishobora kongera guhura na procaine nuburozi bushobora kuba.Kugabanuka k'ibikorwa birashobora kuboneka hamwe no kubura genetike, liverdisease, malignance, imirire mibi, kunanirwa kw'impyiko, gutwika, igihembwe cya gatatu cyo gutwita, no gukurikira indwara ya cardiopulmonary bypasssurgie.Ester hydrolysis itanga PABA, compoundponsponsible reaction ya allergique ihuriweho na anesthetike ya theester.Procaine ntabwo ikoreshwa cyane kuberako idashobora kunyura mumyanya ya lipide ugasanga ikoreshwa nka aninfiltration agent ya caneane cyangwa mucous membrane, forshort nzira.Procaine ikoreshwa kandi kuri nerblock ya periferique kandi nkigikoresho cya epidural kugirango isuzume syndromes yububabare.