Phenibut CAS: 1078-21-3 TIMTEC-BB SBB001567 PHENIBUT

Application:
4-amino-3-phenylbutyrate hydrochloride, which is often used in the preparation of antidepressants, is a very important pharmaceutical intermediate, which can be used in laboratory research and development process and chemical pharmaceutical production process.
Preparation:
(1) From benzoyl chloride and ethyl acetoacetate as raw materials, through condensation and hydrolysis of ethyl benzoyl acetate, then benzaldehyde and nitromethane condensation to produce trans-nitrostyrene, and then the two Micheal addition, the addition of Rennie nickel catalytic hydrogenation, and finally in concentrated hydrochloric acid Chemicalbook hydrolyzed into fenibute.
Biological activity:
Phenibut (Aminophenylbutyricacid Fenibut, Phenigam Phenybut, PhGABA, beta - Phenyl - gamma aminobutyricacid, beta - Phenyl - GABA), as GABA analogs, It is a sedative that targets the central nervous system and has anti-anxiety and sedative effects