I-Prestinoic Acid CAS:35748-51-7 CYS-TYR-PHE-GLN-ASN-CYS(DISULFIDE BRIDGE CYS1-CYS6)

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INOMBOLO YE-CAS:35748-51-7

Igama:I-Prestinoic Acid

Ifomula yekhemikhali:I-C33H42N8O10S2

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I-Molar mass:774.86

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Ukusetshenziswa

I-Prestinoic acid iyi-fatty acid ekhonjiswe ukuthi isebenze njengomphikisi onamandla we-GABAA receptor.Ivimbela umsebenzi we-locomotor futhi ibangele ukuquleka ezilwaneni.I-Prestinoic acid iphinde ibe inhibitor yezifo ezithathelwanayo njenge-herpes, umkhuhlane, namarabi.Le nhlanganisela ibophezela ku-adenine nucleotide ku-receptor ye-GABAA futhi ivimbela ama-ion e-chloride ukuthi angangeni esitokisini ngokuvimbela ukungena kwamanzi.Ukusebenzisana kwe-pressinoic acid ne-GABAA receptor kuvimbela umsebenzi we-neuronal ovimbelayo, okuholela ekubanjweni.I-Prestinoic acid ingasetshenziswa ekwelapheni isithuthwane, isifo sikaParkinson kanye nezinye iziyaluyalu zezinzwa.I-Prestinoic acid iyi-agonist enamandla ye-GABAA receptor engatholakala kumahomoni e-peptide afana ne-vasopressin (i-antidiuretic hormone).Ihlanganiswa ngokwakhiwa kwebhondi ye-disulfide phakathi kwezinsalela ezimbili ze-cysteine kulandelana kwayo kwe-amino acid.Idatha ye-X-ray diffraction yembuliwe