Pressinoic Acid CAS:35748-51-7 CYS-TYR-PHE-GLN-ASN-CYS(DISULFIDE BRIDGE CYS1-CYS6)

I-Prestinoic acid i-fatty acid ebonakaliswe ukuba isebenze njengomchasi onamandla we-GABAA receptor.Ithintela umsebenzi we-locomotor kwaye ibangela ukubanjwa kwezilwanyana.I-Prestinoic acid nayo i-inhibitor yezifo ezithathelwanayo ezifana ne-herpes, umkhuhlane, kunye ne-rabies.Le ngqungquthela ibophelela kwi-adenine nucleotide kwi-receptor ye-GABAA kwaye ivimbela i-chloride ion ukuba ingene kwiseli ngokuvimbela ukunyanzeliswa kwamanzi.Ukusebenzisana kwe-pressinoic acid kunye ne-GABAA receptor inhibitory inhibitory neuronal umsebenzi, okhokelela ekubanjweni.I-Prestinoic acid ingasetyenziselwa ukunyanga isifo sokuxhuzula, isifo sikaParkinson kunye nezinye izifo zemithambo-luvo.I-Prestinoic acid yi-agonist enamandla ye-receptor ye-GABAA enokufumaneka kwi-peptide hormones ezifana ne-vasopressin (i-antidiuretic hormone).Idityaniswe ngokubunjwa kwe-disulfide bond phakathi kweentsalela ezimbini ze-cysteine ​​​​kulandelelwano lwe-amino acid.Idatha ye-X-ray diffraction ibonakalisile