Pressinoic Acid CAS:35748-51-7 CYS-TYR-PHE-GLN-ASN-CYS(DISULFIDE BRIDGE CYS1-CYS6)

ʻO ka waika Pressinoic kahi momona momona i hōʻike ʻia e hana ma ke ʻano he antagonist ikaika o ka loaʻa GABAA.Kāohi ia i ka hana locomotor a hoʻoulu i nā holoholona.ʻO ka waika Pressinoic kekahi mea pale i nā maʻi maʻi e like me ka herpes, influenza, a me ka rabies.Hoʻopili kēia pūhui i ka nucleotide adenine ma ka loaʻa ʻana o GABAA a pale i nā ion chloride mai ke komo ʻana i ke kelepona ma ke kāohi ʻana i ka wai permeability.ʻO ka pilina o ka waika pressinoic me ka mea hoʻokipa GABAA e kāohi i ka hana neuronal inhibitory, kahi e alakaʻi ai i ka hopu.Hiki ke hoʻohana ʻia ka Pressinoic acid no ka mālama ʻana i ka epilepsy, ka maʻi Parkinson a me nā maʻi neurological ʻē aʻe.ʻO ka waika Pressinoic kahi agonist ikaika o ka loaʻa GABAA hiki ke loaʻa i nā hormones peptide e like me vasopressin (antidiuretic hormone).Hoʻohui ʻia ʻo ia e ka hoʻokumu ʻana i ka paʻa disulfide ma waena o ʻelua koena cysteine ​​i kāna kaʻina amino acid.Ua hōʻike ʻia ka ʻikepili diffraction X-ray