Pressinoic Acid CAS: 35748-51-7 CYS-TYR-PHE-GLN-ASN-CYS (DISULFIDE BRIDGE CYS1-CYS6)

Pressinoic acid yog ib tug fatty acid uas tau pom los ua ib tug muaj zog antagonist ntawm GABAA receptor.Nws inhibits locomotor kev ua si thiab ua rau qaug dab peg hauv cov tsiaj.Pressinoic acid kuj yog ib qho inhibitor ntawm cov kab mob xws li herpes, influenza, thiab rabies.Cov tshuaj no khi rau adenine nucleotide ntawm GABAA receptor thiab tiv thaiv chloride ions los ntawm lub cell los ntawm inhibiting dej permeability.Kev sib cuam tshuam ntawm pressinoic acid nrog GABAA receptor inhibits inhibitory neuronal kev ua haujlwm, uas ua rau qaug dab peg.Pressinoic acid yuav siv tau rau kev kho mob qaug dab peg, Parkinson's disease thiab lwm yam kab mob neurological.Pressinoic acid yog lub zog agonist ntawm GABAA receptor uas tuaj yeem pom hauv peptide cov tshuaj hormones xws li vasopressin (antidiuretic hormone).Nws yog synthesized los ntawm disulfide daim ntawv cog lus ntawm ob cysteine ​​residues nyob rau hauv nws cov amino acid ib theem zuj zus.X-ray diffraction cov ntaub ntawv tau qhia