Somatostatin CAS: 51110-01-1 panhibin Anti-Somatostatin HUMAN, PORCINE PORCINE MOUSE 2ACOH 6H2O
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Isticmaalka
Somatostatin, oo sidoo kale loo yaqaan hormoonka xakameynaya hormoonka koritaanka (GIH) ama dhowr magacyo kale, waa hoormoon peptide ah kaas oo nidaamiya nidaamka endocrine wuxuuna saameeyaa neurotransmission iyo kordhinta unugyada iyadoo la falgalaya G-protein-ku-xirnaanta somatostatin receptors iyo joojinta sii deynta noocyo kala duwan oo hormoonnada.Hormoonnada labaad.Somatostatin waxay joojisaa insulinta iyo dheecaanka glucagon.
Somatostatin waxay ku timaadaa laba nooc oo firfircoon, oo ay soo saarto goynta beddelka ah ee hal farcan: mid ka kooban 14 amino acids (oo lagu muujiyey sanduuqa macluumaadka ee midigta), iyo kan kale oo ka kooban 28 amino acids.
Laf-dhabarta, waxa jira lix hidde-side somatostatin oo kala duwan, kuwaas oo lagu kala magacaabo SS1, SS2, SS3, SS4, SS5, iyo SS6.Zebrafish wuxuu leeyahay dhammaan lix.Lix hidde oo kala duwan, oo ay weheliyaan shan somatostatin reseptors oo kala duwan, ayaa somatostatin siinayaa hawlo kala duwan oo kala duwan.Bini'aadamku waxay leeyihiin hal hidde-side somatostatin, SST.
habdhiska dheefshiidka
Somatostatin waxaa soo daaya unugyada delta meelo badan oo ka mid ah habka dheefshiidka, kuwaas oo ah sinuses pyloric, duodenum, iyo jasiiradaha.
Somatostatin oo ay sii daayaan sinuses-ka pyloric waxa ay ka galaa wadnaha nidaamka portal ka ka dibna waxa uu galaa wareegga nidaamka ilaa goobta xannibaadda.Intaa waxaa dheer, somatostatin oo ay sii daayaan unugyada δ waxay u shaqeyn karaan hab paracrine ah.
Caloosha, somatostatin waxay si toos ah ugu shaqeysaa unugyada parietal ee soo saara aashitada iyada oo loo marayo soo-dhoweeyayaasha G-protein-ku-xidhan yahay (taas oo joojisa adenylate cyclase oo sidaas darteed si wax ku ool ah uga soo horjeeda kicinta histamine) si loo yareeyo dheecaanka acid gastric.Somatostatin waxa kale oo ay si wax ku ool ah u hoos u dhigtaa habka dheefshiidka iyada oo si dadban u yaraynaysa wax soo saarka aashitada caloosha iyada oo xannibaysa sii daynta hormoonnada kale sida gastrin iyo histamine.
