CAS: 38304-91-5 Minoxidil alostil lonolox

Hoʻolauna

ʻO Minoxidil, i ʻike ʻia ʻo ka idine puʻe lōʻihi, Minoxidil, molecular formula a me ke kaumaha molekala pili C9H15N5O = 209.25, he keʻokeʻo a keʻokeʻo crystalline pauka, hiki ke hoʻoheheʻe ʻia i ka wai a i ʻole chloroform, hiki ke hoʻoheheʻe ʻia i ka ethanol, hiki ke hoʻoheheʻe ʻia i ka acetone, hiki ke hoʻoheheʻe ʻia i ka acetic acid.Hiki iā ia ke hana pololei i ka paia o ke kīʻaha koko, hoʻomāhuahua i nā arterioles, hoʻemi i ke kūʻē peripheral, hoʻemi i ke koko, a hoʻonui i ka puʻuwai a me ka puka ʻana o ka naʻau.Eia nō naʻe, ʻoi aku ka nui o kāna hopena antihypertensive ma mua o ka hydrazine.

Ka hopena lāʻau lapaʻau

Hoʻonui pololei ʻo Minoxidil i nā arterioles, a laila e hōʻemi i ke kahe koko, akā ʻaʻole ʻike ʻia ke ʻano pololei.ʻAʻole hoʻonui kēia huahana i nā venules.ʻO ka hoʻemi ʻana i ka pale ʻana i nā ʻāpana āpau e alakaʻi i ka wikiwiki o ka puʻuwai reflex a me ka hoʻonui ʻana i ka naʻau.Hoʻonui ka hana Renin ma hope o ka hypotension, ka hopena i ka paʻa ʻana o ka wai a me ka sodium.ʻAʻole hoʻopilikia kēia huahana i ka mīkini vascular Chemicalbook reflex, no laila ʻaʻole hiki mai ka hypotension orthostatic.ʻO Minoxidil kahi lāʻau lapaʻau maʻamau a maikaʻi no ka mālama ʻana i ka nalowale o ka lauoho, akā ʻaʻole maopopo loa kona hopena pharmacological a me nā cell target.I nā makahiki i hala iho nei, ua hōʻike ʻia nā haʻawina e hiki i ka Minoxidil ke hoʻoikaika i ka ulu ʻana o ka lauoho ma o nā ala aʻe.

He lāʻau lapaʻau waha i hoʻohana ʻia i ka lāʻau lapaʻau e hoʻohaʻahaʻa i ke koko

ʻO ka Minoxidil kahi ʻano lāʻau lapaʻau waha i hoʻohana ʻia no ka hoʻohaʻahaʻa ʻana i ke koko ma ke keʻena keʻena, ʻike ʻia ʻo Changbaridine, piperazine enediamine, hypotenidine a me Minlohemoidine.Aia ia i ka mea wehe ʻana i ke kahawai potassium, hiki iā ia ke hoʻomaha pololei i ka ʻiʻo maʻemaʻe vascular a loaʻa kahi hopena dilatation liʻiliʻi liʻiliʻi, e hōʻemi ana i ke kūʻē peripheral, dilatation vascular a me ke kahe koko, akā ʻaʻohe hopena i nā kīʻaha volume, no laila hiki iā ia ke hāpai i ka hoʻihoʻi venous.I ka manawa like, hiki ke hoʻonui ʻia ka puʻuwai puʻuwai a me ka puʻuwai puʻuwai ma muli o ka hoʻoponopono reflex a me ka hopena alapine maikaʻi, akā ʻaʻole ia e hoʻoulu i ka postural hypotension.Hoʻohana ʻia i ka lāʻau lapaʻau i ka mālama ʻana i ka hypertension refractory a me ka hypertension renal.Hiki ke hoʻohana ʻia no ka hypertension koʻikoʻi me ka pane maikaʻi ʻole i nā lāʻau antihypertensive ʻē aʻe, akā pono e hui pū ʻia me nā diuretics e pale aku i ka wai a me ka paʻa sodium.Ke hui pū ʻia me nā lāʻau lapaʻau β-blocking, hiki ke hoʻonui ʻia kona pono a hoʻemi ʻia nā hopena ʻino.ʻO kekahi hopena ʻaoʻao o ka hoʻohana lōʻihi ʻana i ka Minoxidil a me Chemicalbook ʻo ia ka piʻi iki ʻana o ka lauoho kino me ka hoʻohana mau ʻana i ka lāʻau lapaʻau, e like me ka lauoho lima.Akā ma ka laulā ma loko o nā palena kūpono.ʻO nā hopena koʻikoʻi nui o ka hoʻokele waha e pili ana i ka loaʻa ʻana o ke kaumaha a me ka edema limb liʻiliʻi ma muli o ka paʻa ʻana o ka wai a me ka sodium, palpitation a me arrhythmia i hoʻokumu ʻia e ka reflex sympathetic nerve excitation, a me ka hirsuism.ʻO nā hopena koʻikoʻi nui o ka hoʻomākaukau topical ʻo ka ʻili ʻili, erythema, pruritus a me nā hopena dermatitis ʻē aʻe.ʻOiai he liʻiliʻi loa ka nui o ka absorption i loko o ka hoʻomākaukau topical, ʻaʻole hiki ke hoʻokuʻu ʻia i ka hopena o ke ʻano o nā maʻi me ka mōʻaukala o ka maʻi puʻuwai.ʻO nā mea maʻi me ka maʻi cerebrovascular, ka puʻuwai puʻuwai ʻaʻole i hoʻokumu ʻia e ka hypertension, ka maʻi naʻau coronary, angina pectoris, myocardial infarction, pericardial effusion, renal dysfunction a me nā maʻi ʻē aʻe e pono e hoʻohana pono ʻia, pono e hoʻohana pono ʻia ka minoxidil allergy a me nā maʻi pheochromocytoma.