GHRP-6 CAS: 87616-84-0 Homona ulu e hoʻokuʻu ana i ka peptide

Growth hormone-releasing peptide 6 (GHRP-6) (developmental code name SKF-110679), i ʻike ʻia ʻo growth hormone-releasing hexapeptide, ʻo ia kekahi o nā analogues synthetic met-enkephalin e komo pū ana me nā waikona D-amino kūlohelohe, i kūkulu ʻia no kā lākou ka hoʻokuʻu ʻana i ka hormone ulu a ua kapa ʻia ʻo growth hormone secretagogues.ʻAʻole lākou i ka hana opioid akā he mea hoʻoikaika ikaika i ka hoʻokuʻu ʻana i ka hormone ulu.He ʻokoʻa kēia mau secretagogues mai ka ulu ʻana o ka hormone hoʻokuʻu i ka hormone no ka mea ʻaʻole lākou e kaʻana like i ka pilina pili a loaʻa i kā lākou hana ma o ka hoʻāla ʻana o kahi mea loaʻa ʻokoʻa loa.Ua kapa mua ʻia kēia mea hoʻokipa ʻo ka growth hormone secretagogue receptor, akā ma muli o nā ʻike ma hope, ua manaʻo ʻia ka hormone ghrelin i kēia manawa he ligand endogenous maoli o ka receptor, a ua kapa ʻia ʻo ia ʻo ka ghrelin receptor.No laila, hana kēia mau agonists GHSR ma ke ʻano he synthetic ghrelin mimetics.

Ua ʻike ʻia ke lawelawe ʻia ka GHRP-6 a me ka insulin i ka manawa like, hoʻonui ʻia ka pane ʻana o GH i ka GHRP-6.Eia nō naʻe, ʻo ka ʻai ʻana i nā mea momona a me / a i ʻole nā ​​​​momona meaʻai, a puni ka puka makani hoʻomalu o GH secretagogues e hoʻopau nui i ka hoʻokuʻu ʻana o GH.Ua hōʻike ʻia kahi noiʻi hou i nā ʻiole maʻamau i nā ʻokoʻa nui i ka hoʻohui ʻana o ke kino, ka ulu ʻana o ka ʻiʻo, ka metabolism glucose, ka hoʻomanaʻo a me ka hana naʻau i nā ʻiole e lawelawe ʻia ana i ka GHRP-6.Nui nā nīnau e pili ana i kēia pūhui hou.