I-Myomodulin CAS: 110570-93-9 H-Pro-Met-Ser-Met-Leu-Arg-Leu-NH2

incazelo emfushane:

INOMBOLO YE-CAS:110570-93-9

Igama:I-Myomodulin

Ifomula yekhemikhali:I-C36H67N11O8S2

ifomu:impushana

ukuminyana :1.38±0.1 g/cm3(Kubikezelwe)

pka:12.79±0.46(Okubikezelwe)

Izinga lokushisa lokulondoloza:−20°C

I-Molar mass:846.11600

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Ukusetshenziswa

I-Neuropeptide myodulin, i-peptide encane esebenzayo yenhliziyo (SCP) kanye namaprotheni e-buccal asatshalaliswa kabanzi ku-phylum mollusca futhi anemisebenzi ebalulekile yomzimba.Lapha sichaza ukusatshalaliswa okuningiliziwe kwekilasi ngalinye le-peptide ohlelweni lwezinzwa olumaphakathi (CNS) lwe-Lymnaea stagnalis ngokusebenzisa amasu e-immunocytochemical ahlanganiswe nokulebula kodayi kwama-neurons ahlonzwa i-electrophysiology.Sibika ngokuhlukaniswa nokuhlukaniswa kwabalingiswa besakhiwo be-A Lymnaomodulin PMSMLRLamide, efanayo ne-myomodulin A evela kunogwaja wasolwandle.I-Myomodulin immunoreactivity itholakala kuwo wonke ama-ganglia angu-11, izicubu zawo ezixhumeneyo, kanye nezinzwa ezizungezile.Ezimweni eziningi, i-myomodulin immunoreactivity ibonakala kumaqoqo ama-neurons aveza ama-peptide afana ne-FMRFamide, kodwa nakwenani elikhulu lamanye ama-neurons.Ukuhlolwa kokulebula okuphindwe kabili kubonise ukungasebenzi kahle kwe-myomodulin kuma-interneurons amhlophe e-visceral abandakanyeka kumthetho we-cardiopulmonary.I-Scp-like immune reactivity ikhona kuwo wonke ama-ganglia, futhi ukuhlolwa kokulebula okuphindwe kabili kubonisa ukuthi kuhlotshaniswa nokucaciswa kweqoqo lama-exons ahlukene avezwa ngokuhlukile ku-CNS yofuzo lwe-FMRFamide ezindaweni eziningi.Kodwa-ke, izici zama-antiserum amabili e-SCP asetshenziswe kulolu cwaningo ziphakamisa ukuthi zisabela ngokuphambana ne-FMRFamide kanye ne-n-terminal enwetshiwe efana ne-FmrFamide-like peptides.Ukukhethwa kwe-preadsorption kusetshenziswa lawa ma-peptide asebenza ngokuphambanayo kuholele ekususweni kokungcola okubanzi kanye nokugcinwa kokusebenza kabusha kwe-immune kwe-SCP kweqiniso kuphela ku-buccal ne-foot ganglia.I-Buccal protein immunoreactivity yayinqunyelwe ku-buccal kanye ne-foot ganglia.Akuhambisani nokusatshalaliswa kwe-myomodulin noma i-SCP.Amaqoqo amaningi okuphendula amasosha omzimba atholakala ku-foot ganglion.Akuhambisani nokusatshalaliswa kwe-myomodulin noma i-SCP.Amaqoqo amaningi okuphendula amasosha omzimba atholakala ku-foot ganglion.Akuhambisani nokusatshalaliswa kwe-myomodulin noma i-SCP.Amaqoqo amaningi okuphendula amasosha omzimba atholakala ku-foot ganglion.