IHOMONI YOKUKHULA, IZIBONELELO ZOMUNTU: 12629-01-5 HGH
Thinta mina:
Email:salesexecutive1@yeah.net
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I-Human Growthhormone (GH) iyiketango elilodwa, elingenayo i-glycated, i-191 amino acid hydroglobulin enesisindo se-molecular 21700Da kanye ne-isoelectric pI ye-4.9.Kukhona izibopho ze-disulfide phakathi kwezinsalela ze-cysteine kumasayithi 53 kanye ne-165 nasezindaweni ze-182 kanye ne-189. Cishe i-75% ye-hormone yokukhula ekhiqizwe yi-anterior pituitary gland eosinophils ikhiqizwa ngale ndlela yesakhiwo samangqamuzana, kanti enye i-5% kuya ku-10% ikhiqizwe ngesimo sesisindo samangqamuzana angama-20kDa.Ukukhishwa okuzenzakalelayo kwe-hGH kwenzeka ngesimo se-paroxysmal phakathi kwemini nobusuku, futhi ngokuvamile kwenzeka esikhathini sokuqala sokulala segagasi elihamba kancane ngemva kokulala ngokomzimba.Phakathi nosuku, bonke abanye babonakala bekhuthaza ukukhululwa kwe-hGH, kodwa uhlobo lokugcinwa kwe-hGH lwathinteka ngokudla, ukuzila ukudla, ukuvivinya umzimba nokucindezeleka, kodwa isigqi esiyisisekelo asizange sishintshwe.I-secretion amplitude, imvamisa kanye nokugcinwa okuphelele kwe-hGH kuphezulu ebusheni, kuyilapho asebekhulile bephambene nalokho.Izakhiwo I-hormone yokukhula komuntu i-prohormone yakhiwa ama-hormone okukhula ngokwemvelo akhona kumabhaktheriya axhunywe ekuboniseni ama-peptides.I-prohormones ihlukanisa odongeni lwangaphakathi lwamaseli ebhaktheriya, ikhulula umkhiqizo wokugcina ofana ne-hormone yokukhula yemvelo endaweni ye-membrane, bese kuphela udonga lwangaphandle lweseli lubhujiswa ukuze luqoqwe, kuyilapho udonga lwangaphakathi lweseli luhlala luqinile. ukuqinisekisa ukuthi kukhona ukungcoliswa okuncane kwamaprotheni ebhaktheriya omkhiqizo wokugcina.Ulwazi lokuphepha
