HORMONE YAKUKULA, CAS ANTHU: 12629-01-5 HGH

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Human Growthhormone (GH) ndi unyolo umodzi, wopanda glycated, 191 amino acid hydroglobulin wokhala ndi molekyulu yolemera 21700Da ndi isoelectric pI ya 4.9.Pali zomangira za disulfide pakati pa zotsalira za cysteine ​​​​pa malo 53 ndi 165 ndi malo 182 ndi 189. Pafupifupi 75% ya kukula kwa hormone yomwe imatulutsidwa ndi anterior pituitary gland eosinophils imatulutsidwa mu mawonekedwe a maselo, ndipo 5% mpaka 10% ndi zobisika mu mawonekedwe a maselo kulemera 20kDa.Kutulutsa kodziwikiratu kwa hGH kumachitika mu mawonekedwe a paroxysmal pakati pa usana ndi usiku, ndipo nthawi zambiri kumachitika mu nthawi yoyamba yogona pang'onopang'ono pambuyo pogona.Masana, ena onse ankawoneka kuti amalimbikitsa kumasulidwa kwa hGH, koma mawonekedwe achinsinsi a hGH anakhudzidwa ndi kudyetsa, kusala kudya, kuchita masewera olimbitsa thupi ndi kupsinjika maganizo, koma nyimbo yoyamba sinasinthidwe.The secretion amplitude, frequency and total secretion of hGH is high mu unyamata, pamene okalamba ali mosiyana.Katundu Hormoni ya kukula kwaumunthu imapangidwa ndi kukula kwa mahomoni omwe amapezeka mwachibadwa mu mabakiteriya omwe amagwirizanitsidwa ndi zizindikiro za peptides.Ma prohormones amagawikana mkati mwa khoma lamkati la maselo a bakiteriya, kutulutsa chinthu chomaliza chofanana ndi hormone ya kukula kwachilengedwe mu danga la nembanemba, ndiyeno khoma lakunja la selo ndilowonongeka kuti litengedwe, pamene khoma lamkati la selo limakhalabe. kuonetsetsa kuti pali kachilombo kakang'ono ka mapuloteni opangidwa ndi mabakiteriya omwe amathera kumapeto.Zambiri zachitetezo