IHORMONI YOKUKHULA, UMHLA WOMNTU: 12629-01-5 HGH
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I-Human Growthhormone (GH) yitsheyini enye, i-non-glycated, i-191 amino acid hydroglobulin ene-molecular weight 21700Da kunye ne-isoelectric pI ye-4.9.Kukho izibophelelo ze-disulfide phakathi kwe-cysteine i-residus kwiindawo ze-53 kunye ne-165 kunye nakwiindawo ze-182 kunye ne-189. Ngokumalunga ne-75% ye-hormone yokukhula efihliweyo yi-eosinophils yangaphambili ye-pituitary gland ikhutshwe ngolu hlobo lwesakhiwo se-molecular, kunye nenye i-5% ukuya kwi-10% ikhutshelwe ngohlobo lobunzima bemolekyuli 20kDa.Ukukhutshwa okuzenzekelayo kwe-hGH kwenzeka kwimo ye-paroxysmal phakathi kwemini nobusuku, kwaye ngokuqhelekileyo kwenzeka kwixesha lokuqala lokulala elicothayo emva kokulala komzimba.Ngethuba lemini, abanye babonakala bekhuthaza ukukhululwa kwe-hGH, kodwa ifom ye-secretion ye-hGH yachaphazeleka ngokutya, ukuzila ukutya, ukuzivocavoca kunye noxinzelelo, kodwa isigqi esisisiseko asizange sitshintshwe.I-secretion amplitude, i-frequency kunye ne-secretion epheleleyo ye-hGH iphezulu ebusheni, ngelixa abantu abadala bechasene.Iipropathi Ihomoni yokukhula komntu iprohormone yenziwe ngamahomoni okukhula ngokwemvelo akhoyo kwiibhaktheriya ezidityaniswe nokubonisa i-peptides.Iprohormones yahlula kudonga lwangaphakathi lweeseli zebhaktheriya, ikhupha imveliso yokuphela efana nehomoni yokukhula kwendalo kwindawo ye-membrane, kwaye emva koko kuphela udonga lwangaphandle lweseli lutshabalaliswa ukuze luqokelelwe, ngelixa udonga lwangaphakathi lweseli luhlala luqinile. ukuqinisekisa ukuba kukho ungcoliseko oluncinci lweprotheyini yebhaktheriya yemveliso yokugqibela.Ulwazi lokhuseleko
