GUKURA HORMONE, URUBANZA RW'UMUNTU: 12629-01-5 HGH

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Gukura kwa muntu (GH) ni urunigi rumwe, rutarimo glycile, 191 hydroglobuline aside amine ifite uburemere bwa 21700Da na pI isoelectric ya 4.9.Hariho imiyoboro ya disulfide hagati y’ibisigisigi bya sisitemu ku mbuga za 53 na 165 no ku mbuga za 182 na 189. Hafi ya 75% ya hormone yo gukura isohorwa na gland ya pitoito gland eosinophile isohoka muri ubu buryo bwimiterere ya molekile, naho ubundi 5% kugeza 10% ni rwihishwa muburyo bwuburemere bwa molekile 20kDa.Gusohora kwizana kwa HGH bibaho muburyo bwa paroxysmal hagati yumunsi nijoro, kandi mubisanzwe bibaho mugihe cyambere cyo gusinzira gahoro gahoro nyuma yo gusinzira kumubiri.Ku manywa, abasigaye basaga nkaho bateza imbere irekurwa rya HGH, ariko uburyo bwo gusohora hGH bwatewe no kugaburira, kwiyiriza ubusa, gukora siporo no guhangayika, ariko injyana y’ibanze ntabwo yahinduwe.Gusohora kwa amplitude, inshuro nyinshi hamwe no gusohora kwa HGH ni byinshi mubyangavu, mugihe abasaza babihabanye.Ibyiza Imisemburo ikura yumuntu prohormone igizwe na hormone zo gukura zisanzwe ziboneka muri bagiteri zifitanye isano na peptide yerekana ibimenyetso.Porhormone igabanyamo urukuta rw'imbere rw'utugingo ngengabuzima twa bagiteri, ikarekura ibicuruzwa byarangiye bisa na hormone yo gukura bisanzwe mu mwanya wa membrane, hanyuma urukuta rw'inyuma rw'akagari rukaba rwarasenyutse kugira ngo rukusanyirizwe, mu gihe urukuta rw'imbere rw'akagari rukomeza kuba rutameze neza. kwemeza ko hari proteine ​​nkeya zanduza ibicuruzwa byanyuma.Amakuru yumutekano