Nafarelin CAS: 76932-56-4 RS-94991-298 Nasanyl

Nafarelin, e rekisoang ka mabitso a khoebo a kang Synarel, ke gonadotropin e lokollang hormone agonist (GnRH agonist) e sebelisetsoang ho phekola endometriosis le bohlankana ba pele ho nako.E boetse e sebelisoa ho phekola li-fibroids tsa uterine, ho laola ts'ebetso ea mahe a bomme nakong ea in vitro fertilization (IVF), hape e le karolo ea phekolo ea li-hormone tsa thobalano.Moriana ona o sebelisoa e le setlolo sa nko ka makhetlo a mabeli ho isa ho a mararo ka letsatsi.

Litla-morao tsa nafarelin li amahanngoa le ho haelloa ke li-hormone tsa thobalano 'me li kenyelletsa matšoao a maemo a tlaase a testosterone le maemo a tlaase a estrogen, a kang ho chesa ho chesang, ho se sebetse ka thobalano, atrophy ea botšehali le lefu la ho fokola ha masapo.Nafarelin ke gonadotropin-releasing hormone agonist (GnRH agonist) e sebetsang ka ho thibela li-gonads ho hlahisa lihomone tsa thobalano.E ka fokotsa maemo a lihomone tsa thobalano ho batho ba bong ka bobeli ka karolo ea 95 lekholong.Nafarelin ke peptide eo e leng analogue ea GnRH.

Nafarelin e ile ea hlahisoa bakeng sa tšebeliso ea bongaka ka 1990. E sebelisoa haholo lefatšeng ka bophara, ho akarelletsa le Amerika Leboea, Europe, le likarolo tse ling tsa lefats'e.Setlhare ke se seng sa li-analogue tse peli tsa GnRH tse sebelisoang meriana tse fumanehang e le setlolo sa nko, e 'ngoe e le Bucherelin.

Tšebeliso ea bongaka:
Nafarelin e amohetsoe ho phekola endometriosis le ho kena bohlankaneng pele ho nako.E boetse e sebelisoa ho phekola uterine fibroids.Setlhare sena se sebelisetsoa ho laola ts'usumetso ea mahe a bomme nakong ea in vitro fertilization (IVF).Nafarelin e sebelisoa e le thibelo ea bokhachane bakeng sa bacha ba transgender le ho hatella maemo a testosterone ho basali ba transgender.Nafarelin e ka boela ea sebelisoa ho phekola hypertrichosis le polycystic ovary syndrome ka ho fokotsa gonadotropin le maemo a androgen.E sebetsa ho phekola benign prostatic hyperplasia