Nafarelin CAS: 76932-56-4 RS-94991-298 Nasanyl

Nafarelin, wogulitsidwa pansi pa mayina amalonda monga Synarel, ndi gonadotropin release hormone agonist (GnRH agonist) mankhwala omwe amagwiritsidwa ntchito pochiza endometriosis ndi kutha msinkhu.Amagwiritsidwanso ntchito pochiza uterine fibroids, kuwongolera kukondoweza kwa ovarian panthawi ya in vitro fertilization (IVF), komanso ngati gawo la chithandizo chamankhwala ogonana amuna kapena akazi okhaokha.Mankhwalawa amagwiritsidwa ntchito ngati utsi wa m'mphuno kawiri kapena katatu patsiku.

Zotsatira za nafarelin zimagwirizanitsidwa ndi kusowa kwa mahomoni ogonana ndipo zimaphatikizapo zizindikiro za kuchepa kwa testosterone ndi kuchepa kwa estrogen, monga kutentha, kusokonezeka kwa kugonana, atrophy ya vaginal, ndi osteoporosis.Nafarelin ndi gonadotropin-release hormone agonist (GnRH agonist) yomwe imagwira ntchito poletsa ma gonads kupanga mahomoni ogonana.Ikhoza kuchepetsa kuchuluka kwa mahomoni ogonana amuna ndi akazi ndi 95 peresenti.Nafarelin ndi peptide yomwe ndi analogue ya GnRH.

Nafarelin idayambitsidwa kuti igwiritsidwe ntchito pachipatala mu 1990. Imagwiritsidwa ntchito kwambiri padziko lonse lapansi, kuphatikiza North America, Europe, ndi madera ena padziko lapansi.Mankhwalawa ndi amodzi mwa ma analogue awiri a GnRH omwe amagwiritsidwa ntchito pachipatala omwe amapezeka ngati opopera pamphuno, winayo ndi Bucherelin.

Kugwiritsa ntchito kuchipatala:
Nafarelin amavomerezedwa kuchiza endometriosis ndi kutha msinkhu.Amagwiritsidwanso ntchito pochiza uterine fibroids.Mankhwalawa amagwiritsidwa ntchito poletsa kukondoweza kwa ovarian panthawi ya in vitro fertilization (IVF).Nafarelin imagwiritsidwa ntchito ngati choletsa kutha msinkhu kwa achinyamata a transgender komanso kupondereza milingo ya testosterone mwa amayi osintha.Nafarelin angagwiritsidwenso ntchito pochiza hypertrichosis ndi polycystic ovary syndrome pochepetsa gonadotropin ndi androgen.Ndiwothandiza pochiza benign prostatic hyperplasia